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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BPTF All Species: 8.79
Human Site: S1827 Identified Species: 27.62
UniProt: Q12830 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12830 NP_004450.3 3046 338262 S1827 S R P K K T R S G T A L P S Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537586 2823 313566 K1733 K E Y S T R D K V K L M K F S
Cat Felis silvestris
Mouse Mus musculus NP_789820 2921 321579 S1713 S R P K K T R S G T A L P S Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510508 2805 312025 S1705 V G P Y G I R S E Y C I R K I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920272 2758 305936 R1669 L A R R G G I R E V P I F N Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0T1 2669 300667 S1580 P T V G G S T S T Q S N P S T
Honey Bee Apis mellifera XP_395718 2558 287174 S1469 N R N A G S N S G I N D Q L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780572 3453 378739 V2335 Q R R T N D P V R L E K G P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 81.7 N.A. 79.6 N.A. N.A. 69.1 N.A. N.A. 52.8 N.A. 23.6 26.5 N.A. 24.3
Protein Similarity: 100 N.A. N.A. 85.6 N.A. 86.3 N.A. N.A. 76.8 N.A. N.A. 66.2 N.A. 40 42.6 N.A. 42.6
P-Site Identity: 100 N.A. N.A. 0 N.A. 100 N.A. N.A. 20 N.A. N.A. 6.6 N.A. 20 20 N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 6.6 N.A. 100 N.A. N.A. 26.6 N.A. N.A. 26.6 N.A. 33.3 33.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 13 0 0 0 0 0 0 25 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 0 0 0 0 0 13 13 0 0 0 0 13 0 0 0 % D
% Glu: 0 13 0 0 0 0 0 0 25 0 13 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 13 13 0 % F
% Gly: 0 13 0 13 50 13 0 0 38 0 0 0 13 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 13 0 0 13 0 25 0 0 13 % I
% Lys: 13 0 0 25 25 0 0 13 0 13 0 13 13 13 13 % K
% Leu: 13 0 0 0 0 0 0 0 0 13 13 25 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % M
% Asn: 13 0 13 0 13 0 13 0 0 0 13 13 0 13 0 % N
% Pro: 13 0 38 0 0 0 13 0 0 0 13 0 38 13 0 % P
% Gln: 13 0 0 0 0 0 0 0 0 13 0 0 13 0 0 % Q
% Arg: 0 50 25 13 0 13 38 13 13 0 0 0 13 0 0 % R
% Ser: 25 0 0 13 0 25 0 63 0 0 13 0 0 38 13 % S
% Thr: 0 13 0 13 13 25 13 0 13 25 0 0 0 0 13 % T
% Val: 13 0 13 0 0 0 0 13 13 13 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 13 0 0 0 0 0 13 0 0 0 0 38 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _