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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20
All Species:
25.15
Human Site:
S134
Identified Species:
39.52
UniProt:
Q12834
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12834
NP_001246.2
499
54723
S134
E
A
K
I
L
R
L
S
G
K
P
Q
N
A
P
Chimpanzee
Pan troglodytes
XP_513374
499
54758
S134
E
A
K
I
L
R
L
S
G
K
P
Q
N
A
P
Rhesus Macaque
Macaca mulatta
XP_001090604
457
50182
K107
E
G
Y
Q
N
R
L
K
V
L
Y
S
Q
K
A
Dog
Lupus familis
XP_539651
499
54777
S134
E
A
K
I
L
R
L
S
G
K
P
Q
N
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
S134
E
A
K
I
L
R
L
S
G
K
P
Q
N
A
P
Rat
Rattus norvegicus
Q62623
499
54810
S134
E
A
K
I
L
R
L
S
G
K
P
Q
N
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006536
507
56149
S141
E
A
K
I
L
R
L
S
G
K
P
Q
N
A
P
Frog
Xenopus laevis
NP_001079443
506
56086
G141
E
A
K
I
L
R
L
G
G
R
P
Q
N
A
P
Zebra Danio
Brachydanio rerio
NP_998245
496
54922
L135
E
E
A
K
I
L
H
L
G
G
K
P
L
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477501
526
57062
Y160
K
G
G
R
I
L
C
Y
Q
N
K
A
P
A
A
Honey Bee
Apis mellifera
XP_624567
512
57052
Q147
Q
M
R
V
L
S
Y
Q
N
K
A
P
A
P
P
Nematode Worm
Caenorhab. elegans
Q09373
507
56366
A127
L
C
Y
K
K
N
L
A
P
P
P
A
I
G
Y
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
K156
N
S
K
I
L
C
Y
K
N
K
P
P
N
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
K126
S
R
N
I
F
R
F
K
T
E
T
H
R
S
L
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
S213
Q
R
K
G
R
R
L
S
A
A
S
L
L
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.3
97.5
N.A.
94.7
94.9
N.A.
N.A.
80
75
60.5
N.A.
51.3
50.9
24
58.9
Protein Similarity:
100
98.8
91.5
98.4
N.A.
96.9
96.9
N.A.
N.A.
89.9
89.1
76.7
N.A.
66.3
68.9
44.7
74.6
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
100
86.6
13.3
N.A.
6.6
20
13.3
53.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
100
93.3
20
N.A.
20
40
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
7
0
0
0
0
7
7
7
7
14
7
60
20
% A
% Cys:
0
7
0
0
0
7
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
60
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
7
7
0
0
0
7
54
7
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
60
14
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
7
0
60
14
7
0
0
20
0
54
14
0
0
7
0
% K
% Leu:
7
0
0
0
60
14
67
7
0
7
0
7
14
0
7
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
7
7
0
0
14
7
0
0
54
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
7
60
20
7
7
60
% P
% Gln:
14
0
0
7
0
0
0
7
7
0
0
47
7
7
0
% Q
% Arg:
0
14
7
7
7
67
0
0
0
7
0
0
7
0
0
% R
% Ser:
7
7
0
0
0
7
0
47
0
0
7
7
0
7
7
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
0
0
0
14
7
0
0
7
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _