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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC20 All Species: 36.06
Human Site: S153 Identified Species: 56.67
UniProt: Q12834 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12834 NP_001246.2 499 54723 S153 N R L K V L Y S Q K A T P G S
Chimpanzee Pan troglodytes XP_513374 499 54758 S153 N R L K V L Y S Q K A T P G S
Rhesus Macaque Macaca mulatta XP_001090604 457 50182 I126 S R K T C R Y I P S L P D R I
Dog Lupus familis XP_539651 499 54777 S153 N R L K V L Y S Q K A T P G S
Cat Felis silvestris
Mouse Mus musculus Q9JJ66 499 54797 S153 N R L K V L Y S Q K A T P G S
Rat Rattus norvegicus Q62623 499 54810 S153 N R L K V L Y S Q K A T P G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006536 507 56149 S160 N N L K V L Y S Q K T T P A S
Frog Xenopus laevis NP_001079443 506 56086 S160 N N L K V L Y S Q K N T P G S
Zebra Danio Brachydanio rerio NP_998245 496 54922 Y154 Q N N L K V L Y S Q V P T P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477501 526 57062 Y179 N N P L K V V Y S I K T P I S
Honey Bee Apis mellifera XP_624567 512 57052 S166 N P L R V V Y S Q S K T P A S
Nematode Worm Caenorhab. elegans Q09373 507 56366 S146 K V L Y S T N S V I N P A S S
Sea Urchin Strong. purpuratus XP_781780 524 57779 S175 N N L K V M Y S H N K T P G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L3Z8 483 52822 S145 P F G V D D D S P G V S H S G
Baker's Yeast Sacchar. cerevisiae P53197 566 62803 D232 S M S P V R P D S K Q L L L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 91.3 97.5 N.A. 94.7 94.9 N.A. N.A. 80 75 60.5 N.A. 51.3 50.9 24 58.9
Protein Similarity: 100 98.8 91.5 98.4 N.A. 96.9 96.9 N.A. N.A. 89.9 89.1 76.7 N.A. 66.3 68.9 44.7 74.6
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. N.A. 80 86.6 0 N.A. 26.6 60 20 66.6
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. N.A. 80 86.6 13.3 N.A. 33.3 73.3 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. 35.2 33.7 N.A.
Protein Similarity: N.A. N.A. N.A. 52.3 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 34 0 7 14 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 7 7 7 0 0 0 0 7 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 7 0 0 0 47 7 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 14 0 0 0 7 7 % I
% Lys: 7 0 7 54 14 0 0 0 0 54 20 0 0 0 0 % K
% Leu: 0 0 67 14 0 47 7 0 0 0 7 7 7 7 0 % L
% Met: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 67 34 7 0 0 0 7 0 0 7 14 0 0 0 0 % N
% Pro: 7 7 7 7 0 0 7 0 14 0 0 20 67 7 0 % P
% Gln: 7 0 0 0 0 0 0 0 54 7 7 0 0 0 0 % Q
% Arg: 0 40 0 7 0 14 0 0 0 0 0 0 0 7 0 % R
% Ser: 14 0 7 0 7 0 0 74 20 14 0 7 0 14 80 % S
% Thr: 0 0 0 7 0 7 0 0 0 0 7 67 7 0 0 % T
% Val: 0 7 0 7 67 20 7 0 7 0 14 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 67 14 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _