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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC20 All Species: 33.94
Human Site: S231 Identified Species: 53.33
UniProt: Q12834 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12834 NP_001246.2 499 54723 S231 Q P G E Y I S S V A W I K E G
Chimpanzee Pan troglodytes XP_513374 499 54758 S231 Q P G E Y I S S V A W I K E G
Rhesus Macaque Macaca mulatta XP_001090604 457 50182 S204 N Y L A V G T S S A E V Q L W
Dog Lupus familis XP_539651 499 54777 S231 Q P G E Y I S S V A W I K E G
Cat Felis silvestris
Mouse Mus musculus Q9JJ66 499 54797 S231 Q P G D Y I S S V A W I K E G
Rat Rattus norvegicus Q62623 499 54810 S231 Q P G D Y I S S V A W I K E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006536 507 56149 S238 N P D D Y V S S V S W I K E G
Frog Xenopus laevis NP_001079443 506 56086 S238 N S E E Y I S S V S W I K E G
Zebra Danio Brachydanio rerio NP_998245 496 54922 S232 D D N E Y I C S V S W S K D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477501 526 57062 L257 E G D Y A G S L S W I Q E G Q
Honey Bee Apis mellifera XP_624567 512 57052 V244 G N D Y V C S V A W I Q E G P
Nematode Worm Caenorhab. elegans Q09373 507 56366 I224 A P T N E G L I T S V R W S Q
Sea Urchin Strong. purpuratus XP_781780 524 57779 S253 G P E D Y V T S V S W I T E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L3Z8 483 52822 V223 A E D S V C S V G W A L R G T
Baker's Yeast Sacchar. cerevisiae P53197 566 62803 W310 N E Y T S L S W I G A G S H L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 91.3 97.5 N.A. 94.7 94.9 N.A. N.A. 80 75 60.5 N.A. 51.3 50.9 24 58.9
Protein Similarity: 100 98.8 91.5 98.4 N.A. 96.9 96.9 N.A. N.A. 89.9 89.1 76.7 N.A. 66.3 68.9 44.7 74.6
P-Site Identity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. N.A. 66.6 73.3 53.3 N.A. 6.6 6.6 6.6 53.3
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. N.A. 86.6 80 66.6 N.A. 20 13.3 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. 35.2 33.7 N.A.
Protein Similarity: N.A. N.A. N.A. 52.3 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 7 7 0 0 0 7 40 14 0 0 0 0 % A
% Cys: 0 0 0 0 0 14 7 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 27 27 0 0 0 0 0 0 0 0 0 7 0 % D
% Glu: 7 14 14 34 7 0 0 0 0 0 7 0 14 54 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 7 34 0 0 20 0 0 7 7 0 7 0 20 60 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 47 0 7 7 0 14 54 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 54 0 0 % K
% Leu: 0 0 7 0 0 7 7 7 0 0 0 7 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 27 7 7 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 54 0 0 0 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 34 0 0 0 0 0 0 0 0 0 0 14 7 0 14 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % R
% Ser: 0 7 0 7 7 0 74 67 14 34 0 7 7 7 0 % S
% Thr: 0 0 7 7 0 0 14 0 7 0 0 0 7 0 7 % T
% Val: 0 0 0 0 20 14 0 14 60 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 20 60 0 7 0 7 % W
% Tyr: 0 7 7 14 60 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _