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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC20 All Species: 36.06
Human Site: S273 Identified Species: 56.67
UniProt: Q12834 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12834 NP_001246.2 499 54723 S273 S H S A R V G S L S W N S Y I
Chimpanzee Pan troglodytes XP_513374 499 54758 S273 S H S A R V G S L S W N S Y I
Rhesus Macaque Macaca mulatta XP_001090604 457 50182 S243 S Y I L S S G S R S G H I H H
Dog Lupus familis XP_539651 499 54777 S273 G H S A R V S S L C W N S Y I
Cat Felis silvestris
Mouse Mus musculus Q9JJ66 499 54797 S273 S H S A R V S S L S W N S Y I
Rat Rattus norvegicus Q62623 499 54810 S273 S H S A R V S S L S W N S Y I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006536 507 56149 S280 S H S S R V G S L S W N S Y I
Frog Xenopus laevis NP_001079443 506 56086 A280 S H S S R V G A L S W N N H I
Zebra Danio Brachydanio rerio NP_998245 496 54922 C274 G H S A R V G C L S W N D H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477501 526 57062 S298 G H S A R V G S L A W N S F L
Honey Bee Apis mellifera XP_624567 512 57052 S285 G H A A R V G S L S W N S H I
Nematode Worm Caenorhab. elegans Q09373 507 56366 I276 G A S R C A S I A W R K Q G V
Sea Urchin Strong. purpuratus XP_781780 524 57779 S295 G H A A R V G S L S W N S Y I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L3Z8 483 52822 A264 G H R L R V G A L A W G S S V
Baker's Yeast Sacchar. cerevisiae P53197 566 62803 C349 G H I D R V A C L S W N N H V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 91.3 97.5 N.A. 94.7 94.9 N.A. N.A. 80 75 60.5 N.A. 51.3 50.9 24 58.9
Protein Similarity: 100 98.8 91.5 98.4 N.A. 96.9 96.9 N.A. N.A. 89.9 89.1 76.7 N.A. 66.3 68.9 44.7 74.6
P-Site Identity: 100 100 26.6 80 N.A. 93.3 93.3 N.A. N.A. 93.3 73.3 73.3 N.A. 73.3 80 6.6 86.6
P-Site Similarity: 100 100 46.6 80 N.A. 93.3 93.3 N.A. N.A. 100 100 80 N.A. 93.3 93.3 13.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 35.2 33.7 N.A.
Protein Similarity: N.A. N.A. N.A. 52.3 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 14 60 0 7 7 14 7 14 0 0 0 0 0 % A
% Cys: 0 0 0 0 7 0 0 14 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 54 0 0 0 0 0 67 0 0 0 7 7 0 7 0 % G
% His: 0 87 0 0 0 0 0 0 0 0 0 7 0 34 7 % H
% Ile: 0 0 14 0 0 0 0 7 0 0 0 0 7 0 67 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 0 0 14 0 0 0 0 87 0 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 80 14 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 7 7 87 0 0 0 7 0 7 0 0 0 0 % R
% Ser: 47 0 67 14 7 7 27 67 0 74 0 0 67 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 87 0 0 0 0 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 87 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 0 0 47 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _