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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC20 All Species: 27.58
Human Site: S41 Identified Species: 43.33
UniProt: Q12834 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12834 NP_001246.2 499 54723 S41 E A A G P A P S P M R A A N R
Chimpanzee Pan troglodytes XP_513374 499 54758 S41 E A A G P A P S P M R A A N R
Rhesus Macaque Macaca mulatta XP_001090604 457 50182 V25 P G K S S S K V Q T T P S K P
Dog Lupus familis XP_539651 499 54777 S41 E A A G P A P S P M R A A N R
Cat Felis silvestris
Mouse Mus musculus Q9JJ66 499 54797 S41 E A T G P A P S P M R A A N R
Rat Rattus norvegicus Q62623 499 54810 S41 E A T G P A P S P M R A A N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006536 507 56149 S49 P S P A A S M S P M K P A N R
Frog Xenopus laevis NP_001079443 506 56086 S49 S A N T S T M S P M K T S N R
Zebra Danio Brachydanio rerio NP_998245 496 54922 I43 N S S S T N S I S P N K S V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477501 526 57062 N51 S V L S V S Y N T S F S G V Q
Honey Bee Apis mellifera XP_624567 512 57052 S43 N S S V N I N S S R K I S N G
Nematode Worm Caenorhab. elegans Q09373 507 56366 T44 T N L L P N A T F V G D R F L
Sea Urchin Strong. purpuratus XP_781780 524 57779 R57 S P M K M S N R S F G V A K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L3Z8 483 52822 S36 T P V V S L E S R I N R L I N
Baker's Yeast Sacchar. cerevisiae P53197 566 62803 S73 F N S I V S I S S M A S V P A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 91.3 97.5 N.A. 94.7 94.9 N.A. N.A. 80 75 60.5 N.A. 51.3 50.9 24 58.9
Protein Similarity: 100 98.8 91.5 98.4 N.A. 96.9 96.9 N.A. N.A. 89.9 89.1 76.7 N.A. 66.3 68.9 44.7 74.6
P-Site Identity: 100 100 0 100 N.A. 93.3 93.3 N.A. N.A. 40 40 0 N.A. 0 13.3 6.6 6.6
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. N.A. 60 53.3 20 N.A. 26.6 40 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 35.2 33.7 N.A.
Protein Similarity: N.A. N.A. N.A. 52.3 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 20 7 7 34 7 0 0 0 7 34 47 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % D
% Glu: 34 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 7 7 7 0 0 7 0 % F
% Gly: 0 7 0 34 0 0 0 0 0 0 14 0 7 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 7 7 7 0 7 0 7 0 7 0 % I
% Lys: 0 0 7 7 0 0 7 0 0 0 20 7 0 14 0 % K
% Leu: 0 0 14 7 0 7 0 0 0 0 0 0 7 0 7 % L
% Met: 0 0 7 0 7 0 14 0 0 54 0 0 0 0 0 % M
% Asn: 14 14 7 0 7 14 14 7 0 0 14 0 0 54 14 % N
% Pro: 14 14 7 0 40 0 34 0 47 7 0 14 0 7 7 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 0 0 7 7 7 34 7 7 0 47 % R
% Ser: 20 20 20 20 20 34 7 67 27 7 0 14 27 0 0 % S
% Thr: 14 0 14 7 7 7 0 7 7 7 7 7 0 0 7 % T
% Val: 0 7 7 14 14 0 0 7 0 7 0 7 7 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _