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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20
All Species:
26.36
Human Site:
S487
Identified Species:
41.43
UniProt:
Q12834
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12834
NP_001246.2
499
54723
S487
R
R
E
R
E
K
A
S
A
A
K
S
S
L
I
Chimpanzee
Pan troglodytes
XP_513374
499
54758
S487
R
R
E
R
E
K
A
S
A
A
K
S
S
L
I
Rhesus Macaque
Macaca mulatta
XP_001090604
457
50182
A446
R
E
R
E
K
A
S
A
A
K
S
S
L
I
H
Dog
Lupus familis
XP_539651
499
54777
S487
R
R
E
R
E
K
A
S
A
A
K
S
S
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
S487
R
R
E
R
E
K
A
S
V
A
K
S
S
L
I
Rat
Rattus norvegicus
Q62623
499
54810
S487
R
R
E
R
E
K
A
S
T
S
K
S
S
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006536
507
56149
N495
K
K
E
K
E
K
A
N
S
A
K
S
S
I
I
Frog
Xenopus laevis
NP_001079443
506
56086
S494
T
K
K
E
K
E
K
S
R
S
S
K
S
I
I
Zebra Danio
Brachydanio rerio
NP_998245
496
54922
K484
K
D
A
A
K
K
P
K
Q
A
S
G
R
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477501
526
57062
S514
S
K
K
A
V
S
T
S
K
G
K
Q
S
V
F
Honey Bee
Apis mellifera
XP_624567
512
57052
I500
K
K
K
D
T
N
E
I
K
A
V
A
S
R
L
Nematode Worm
Caenorhab. elegans
Q09373
507
56366
I493
N
V
D
K
S
T
N
I
L
D
R
T
A
P
K
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
S507
K
S
K
K
E
K
S
S
S
S
V
K
L
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
S470
P
K
S
Q
N
T
D
S
E
I
G
S
S
F
F
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
N555
P
K
A
K
V
Q
P
N
S
L
I
F
D
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.3
97.5
N.A.
94.7
94.9
N.A.
N.A.
80
75
60.5
N.A.
51.3
50.9
24
58.9
Protein Similarity:
100
98.8
91.5
98.4
N.A.
96.9
96.9
N.A.
N.A.
89.9
89.1
76.7
N.A.
66.3
68.9
44.7
74.6
P-Site Identity:
100
100
20
100
N.A.
93.3
86.6
N.A.
N.A.
60
20
20
N.A.
20
13.3
0
20
P-Site Similarity:
100
100
46.6
100
N.A.
93.3
93.3
N.A.
N.A.
100
60
40
N.A.
40
46.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
14
0
7
40
7
27
47
0
7
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
7
0
0
7
0
0
7
0
0
7
0
0
% D
% Glu:
0
7
40
14
47
7
7
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
20
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
7
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
14
0
7
7
0
0
27
54
% I
% Lys:
27
40
27
27
20
54
7
7
14
7
47
14
0
0
7
% K
% Leu:
0
0
0
0
0
0
0
0
7
7
0
0
14
34
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
7
7
14
0
0
0
0
0
0
0
% N
% Pro:
14
0
0
0
0
0
14
0
0
0
0
0
0
14
0
% P
% Gln:
0
0
0
7
0
7
0
0
7
0
0
7
0
0
0
% Q
% Arg:
40
34
7
34
0
0
0
0
7
0
7
0
7
7
0
% R
% Ser:
7
7
7
0
7
7
14
60
20
20
20
54
67
0
7
% S
% Thr:
7
0
0
0
7
14
7
0
7
0
0
7
0
0
0
% T
% Val:
0
7
0
0
14
0
0
0
7
0
14
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _