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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC20 All Species: 26.97
Human Site: S491 Identified Species: 42.38
UniProt: Q12834 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12834 NP_001246.2 499 54723 S491 E K A S A A K S S L I H Q G I
Chimpanzee Pan troglodytes XP_513374 499 54758 S491 E K A S A A K S S L I H Q G I
Rhesus Macaque Macaca mulatta XP_001090604 457 50182 S450 K A S A A K S S L I H Q G I R
Dog Lupus familis XP_539651 499 54777 S491 E K A S A A K S S L I H Q G I
Cat Felis silvestris
Mouse Mus musculus Q9JJ66 499 54797 S491 E K A S V A K S S L I H Q G I
Rat Rattus norvegicus Q62623 499 54810 S491 E K A S T S K S S L I H Q G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006536 507 56149 S499 E K A N S A K S S I I H Q G I
Frog Xenopus laevis NP_001079443 506 56086 K498 K E K S R S S K S I I H Q S I
Zebra Danio Brachydanio rerio NP_998245 496 54922 G488 K K P K Q A S G R I I Q Q S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477501 526 57062 Q518 V S T S K G K Q S V F R Q S I
Honey Bee Apis mellifera XP_624567 512 57052 A504 T N E I K A V A S R L K Q S I
Nematode Worm Caenorhab. elegans Q09373 507 56366 T497 S T N I L D R T A P K N V G L
Sea Urchin Strong. purpuratus XP_781780 524 57779 K511 E K S S S S V K L P S N S I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L3Z8 483 52822 S474 N T D S E I G S S F F G R T T
Baker's Yeast Sacchar. cerevisiae P53197 566 62803 F559 V Q P N S L I F D A F N Q I R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 91.3 97.5 N.A. 94.7 94.9 N.A. N.A. 80 75 60.5 N.A. 51.3 50.9 24 58.9
Protein Similarity: 100 98.8 91.5 98.4 N.A. 96.9 96.9 N.A. N.A. 89.9 89.1 76.7 N.A. 66.3 68.9 44.7 74.6
P-Site Identity: 100 100 13.3 100 N.A. 93.3 86.6 N.A. N.A. 80 40 33.3 N.A. 33.3 26.6 6.6 20
P-Site Similarity: 100 100 40 100 N.A. 93.3 93.3 N.A. N.A. 100 66.6 46.6 N.A. 40 40 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. 35.2 33.7 N.A.
Protein Similarity: N.A. N.A. N.A. 52.3 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 40 7 27 47 0 7 7 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 0 0 7 0 0 0 0 0 0 % D
% Glu: 47 7 7 0 7 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 7 20 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 7 7 0 0 0 7 7 47 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 47 0 0 0 % H
% Ile: 0 0 0 14 0 7 7 0 0 27 54 0 0 20 67 % I
% Lys: 20 54 7 7 14 7 47 14 0 0 7 7 0 0 0 % K
% Leu: 0 0 0 0 7 7 0 0 14 34 7 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 7 14 0 0 0 0 0 0 0 20 0 0 0 % N
% Pro: 0 0 14 0 0 0 0 0 0 14 0 0 0 0 0 % P
% Gln: 0 7 0 0 7 0 0 7 0 0 0 14 74 0 0 % Q
% Arg: 0 0 0 0 7 0 7 0 7 7 0 7 7 0 14 % R
% Ser: 7 7 14 60 20 20 20 54 67 0 7 0 7 27 7 % S
% Thr: 7 14 7 0 7 0 0 7 0 0 0 0 0 7 7 % T
% Val: 14 0 0 0 7 0 14 0 0 7 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _