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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC20 All Species: 25.15
Human Site: S63 Identified Species: 39.52
UniProt: Q12834 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12834 NP_001246.2 499 54723 S63 P G R T P G K S S S K V Q T T
Chimpanzee Pan troglodytes XP_513374 499 54758 S63 P X X X P P R S S S K V Q T T
Rhesus Macaque Macaca mulatta XP_001090604 457 50182 E47 H R S A A Q M E V A S F L L S
Dog Lupus familis XP_539651 499 54777 S63 P G R T P G K S S S K A Q T T
Cat Felis silvestris
Mouse Mus musculus Q9JJ66 499 54797 S63 P G R T P G K S S S K V Q T T
Rat Rattus norvegicus Q62623 499 54810 S63 P G R T P G K S N S K V Q T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006536 507 56149 S71 P S K T P G K S G S K V Q S T
Frog Xenopus laevis NP_001079443 506 56086 S71 P S K T P G K S G Q K M Q G T
Zebra Danio Brachydanio rerio NP_998245 496 54922 K65 T P S K T P G K N G K T Q N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477501 526 57062 K73 K S S E G K T K K S N T T P S
Honey Bee Apis mellifera XP_624567 512 57052 N65 G K T P T K K N D N R T K K S
Nematode Worm Caenorhab. elegans Q09373 507 56366 L66 E L D H A N H L M T S K L Y S
Sea Urchin Strong. purpuratus XP_781780 524 57779 G79 T I R S K T P G K G K S K T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L3Z8 483 52822 S58 S P S S L S R S I Y S D R F I
Baker's Yeast Sacchar. cerevisiae P53197 566 62803 E95 D Q V E Y Q K E R Q A H E T Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 91.3 97.5 N.A. 94.7 94.9 N.A. N.A. 80 75 60.5 N.A. 51.3 50.9 24 58.9
Protein Similarity: 100 98.8 91.5 98.4 N.A. 96.9 96.9 N.A. N.A. 89.9 89.1 76.7 N.A. 66.3 68.9 44.7 74.6
P-Site Identity: 100 66.6 0 93.3 N.A. 100 93.3 N.A. N.A. 73.3 60 20 N.A. 6.6 6.6 0 20
P-Site Similarity: 100 73.3 13.3 93.3 N.A. 100 100 N.A. N.A. 86.6 73.3 26.6 N.A. 13.3 40 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 35.2 33.7 N.A.
Protein Similarity: N.A. N.A. N.A. 52.3 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 14 0 0 0 0 7 7 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 0 0 0 7 0 0 7 0 0 0 % D
% Glu: 7 0 0 14 0 0 0 14 0 0 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % F
% Gly: 7 27 0 0 7 40 7 7 14 14 0 0 0 7 0 % G
% His: 7 0 0 7 0 0 7 0 0 0 0 7 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 7 % I
% Lys: 7 7 14 7 7 14 54 14 14 0 60 7 14 7 0 % K
% Leu: 0 7 0 0 7 0 0 7 0 0 0 0 14 7 0 % L
% Met: 0 0 0 0 0 0 7 0 7 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 7 14 7 7 0 0 7 0 % N
% Pro: 47 14 0 7 47 14 7 0 0 0 0 0 0 7 7 % P
% Gln: 0 7 0 0 0 14 0 0 0 14 0 0 54 0 0 % Q
% Arg: 0 7 34 0 0 0 14 0 7 0 7 0 7 0 0 % R
% Ser: 7 20 27 14 0 7 0 54 27 47 20 7 0 7 27 % S
% Thr: 14 0 7 40 14 7 7 0 0 7 0 20 7 47 54 % T
% Val: 0 0 7 0 0 0 0 0 7 0 0 34 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 7 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _