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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20
All Species:
27.27
Human Site:
S92
Identified Species:
42.86
UniProt:
Q12834
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12834
NP_001246.2
499
54723
S92
A
A
Q
M
E
V
A
S
F
L
L
S
K
E
N
Chimpanzee
Pan troglodytes
XP_513374
499
54758
S92
A
A
Q
M
R
V
A
S
F
L
X
S
K
E
N
Rhesus Macaque
Macaca mulatta
XP_001090604
457
50182
L76
E
H
Q
K
A
W
A
L
N
L
N
G
F
D
V
Dog
Lupus familis
XP_539651
499
54777
S92
A
S
Q
M
E
V
A
S
F
L
L
S
K
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
S92
A
S
Q
M
E
V
A
S
F
L
L
S
K
E
N
Rat
Rattus norvegicus
Q62623
499
54810
S92
A
S
Q
M
E
V
A
S
F
L
L
S
K
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006536
507
56149
N100
T
M
Q
M
E
M
A
N
F
L
L
T
K
E
N
Frog
Xenopus laevis
NP_001079443
506
56086
S100
A
M
Q
M
D
V
A
S
F
L
L
S
K
E
N
Zebra Danio
Brachydanio rerio
NP_998245
496
54922
S94
N
K
Q
L
D
V
A
S
F
L
I
S
K
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477501
526
57062
H102
A
T
N
F
E
L
A
H
F
L
V
N
K
D
S
Honey Bee
Apis mellifera
XP_624567
512
57052
N94
I
P
S
R
S
T
T
N
F
D
L
G
Y
Y
K
Nematode Worm
Caenorhab. elegans
Q09373
507
56366
G95
P
E
K
K
S
V
E
G
E
A
L
K
Q
M
M
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
N108
A
T
N
F
D
L
G
N
F
K
L
Q
D
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
K87
P
S
P
S
K
D
G
K
E
D
G
A
G
S
Y
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
S124
K
D
T
V
G
S
E
S
S
I
D
R
I
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.3
97.5
N.A.
94.7
94.9
N.A.
N.A.
80
75
60.5
N.A.
51.3
50.9
24
58.9
Protein Similarity:
100
98.8
91.5
98.4
N.A.
96.9
96.9
N.A.
N.A.
89.9
89.1
76.7
N.A.
66.3
68.9
44.7
74.6
P-Site Identity:
100
86.6
20
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
86.6
66.6
N.A.
40
13.3
13.3
20
P-Site Similarity:
100
86.6
26.6
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
86.6
N.A.
73.3
20
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
14
0
0
7
0
67
0
0
7
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
20
7
0
0
0
14
7
0
7
14
0
% D
% Glu:
7
7
0
0
40
0
14
0
14
0
0
0
0
54
0
% E
% Phe:
0
0
0
14
0
0
0
0
74
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
7
0
14
7
0
0
7
14
7
0
0
% G
% His:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
7
7
0
7
0
0
% I
% Lys:
7
7
7
14
7
0
0
7
0
7
0
7
60
7
7
% K
% Leu:
0
0
0
7
0
14
0
7
0
67
60
0
0
0
0
% L
% Met:
0
14
0
47
0
7
0
0
0
0
0
0
0
7
7
% M
% Asn:
7
0
14
0
0
0
0
20
7
0
7
7
0
0
60
% N
% Pro:
14
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
60
0
0
0
0
0
0
0
0
7
7
7
0
% Q
% Arg:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
27
7
7
14
7
0
54
7
0
0
47
0
7
14
% S
% Thr:
7
14
7
0
0
7
7
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
7
0
54
0
0
0
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _