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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20
All Species:
16.97
Human Site:
T106
Identified Species:
26.67
UniProt:
Q12834
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12834
NP_001246.2
499
54723
T106
N
Q
P
E
N
S
Q
T
P
T
K
K
E
H
Q
Chimpanzee
Pan troglodytes
XP_513374
499
54758
T106
N
Q
P
E
N
S
Q
T
P
T
K
K
E
H
Q
Rhesus Macaque
Macaca mulatta
XP_001090604
457
50182
R90
V
E
E
A
K
I
L
R
L
S
G
K
P
Q
N
Dog
Lupus familis
XP_539651
499
54777
T106
N
Q
P
E
E
S
H
T
P
T
K
K
E
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
T106
N
Q
P
E
D
R
G
T
P
T
K
K
E
H
Q
Rat
Rattus norvegicus
Q62623
499
54810
T106
N
Q
P
E
D
G
G
T
P
T
K
K
E
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006536
507
56149
P114
N
D
P
A
E
N
S
P
T
K
K
E
Q
Q
K
Frog
Xenopus laevis
NP_001079443
506
56086
P114
N
E
P
T
D
T
S
P
T
K
K
E
Q
Q
K
Zebra Danio
Brachydanio rerio
NP_998245
496
54922
E108
N
E
P
V
E
E
S
E
P
S
T
A
P
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477501
526
57062
E116
S
G
D
K
S
D
E
E
N
D
K
A
T
S
S
Honey Bee
Apis mellifera
XP_624567
512
57052
A108
K
I
Q
Q
Q
T
N
A
E
K
D
E
E
K
L
Nematode Worm
Caenorhab. elegans
Q09373
507
56366
A109
M
R
H
K
S
T
G
A
L
T
D
A
D
D
G
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
T122
S
T
N
I
G
E
N
T
D
P
A
L
M
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
A101
Y
A
T
L
L
R
A
A
M
F
G
P
E
T
P
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
G138
N
T
R
P
S
T
R
G
N
V
H
A
E
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.3
97.5
N.A.
94.7
94.9
N.A.
N.A.
80
75
60.5
N.A.
51.3
50.9
24
58.9
Protein Similarity:
100
98.8
91.5
98.4
N.A.
96.9
96.9
N.A.
N.A.
89.9
89.1
76.7
N.A.
66.3
68.9
44.7
74.6
P-Site Identity:
100
100
6.6
86.6
N.A.
80
80
N.A.
N.A.
20
20
26.6
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
100
20
86.6
N.A.
86.6
86.6
N.A.
N.A.
46.6
60
46.6
N.A.
33.3
26.6
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
14
0
0
7
20
0
0
7
27
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
20
7
0
0
7
7
14
0
7
7
0
% D
% Glu:
0
20
7
34
20
14
7
14
7
0
0
20
54
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
7
20
7
0
0
14
0
0
0
7
% G
% His:
0
0
7
0
0
0
7
0
0
0
7
0
0
34
0
% H
% Ile:
0
7
0
7
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
14
7
0
0
0
0
20
54
40
0
7
14
% K
% Leu:
0
0
0
7
7
0
7
0
14
0
0
7
0
0
7
% L
% Met:
7
0
0
0
0
0
0
0
7
0
0
0
7
7
0
% M
% Asn:
60
0
7
0
14
7
14
0
14
0
0
0
0
14
7
% N
% Pro:
0
0
54
7
0
0
0
14
40
7
0
7
14
0
7
% P
% Gln:
0
34
7
7
7
0
14
0
0
0
0
0
14
20
40
% Q
% Arg:
0
7
7
0
0
14
7
7
0
0
0
0
0
0
0
% R
% Ser:
14
0
0
0
20
20
20
0
0
14
0
0
0
7
14
% S
% Thr:
0
14
7
7
0
27
0
40
14
40
7
0
7
7
7
% T
% Val:
7
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _