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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20
All Species:
34.85
Human Site:
T157
Identified Species:
54.76
UniProt:
Q12834
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12834
NP_001246.2
499
54723
T157
V
L
Y
S
Q
K
A
T
P
G
S
S
R
K
T
Chimpanzee
Pan troglodytes
XP_513374
499
54758
T157
V
L
Y
S
Q
K
A
T
P
G
S
S
R
K
T
Rhesus Macaque
Macaca mulatta
XP_001090604
457
50182
P130
C
R
Y
I
P
S
L
P
D
R
I
L
D
A
P
Dog
Lupus familis
XP_539651
499
54777
T157
V
L
Y
S
Q
K
A
T
P
G
S
T
R
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
T157
V
L
Y
S
Q
K
A
T
P
G
S
S
R
K
T
Rat
Rattus norvegicus
Q62623
499
54810
T157
V
L
Y
S
Q
K
A
T
P
G
S
S
R
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006536
507
56149
T164
V
L
Y
S
Q
K
T
T
P
A
S
S
R
K
H
Frog
Xenopus laevis
NP_001079443
506
56086
T164
V
L
Y
S
Q
K
N
T
P
G
S
S
K
K
T
Zebra Danio
Brachydanio rerio
NP_998245
496
54922
P158
K
V
L
Y
S
Q
V
P
T
P
V
S
V
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477501
526
57062
T183
K
V
V
Y
S
I
K
T
P
I
S
T
K
S
G
Honey Bee
Apis mellifera
XP_624567
512
57052
T170
V
V
Y
S
Q
S
K
T
P
A
S
I
K
T
S
Nematode Worm
Caenorhab. elegans
Q09373
507
56366
P150
S
T
N
S
V
I
N
P
A
S
S
V
K
K
S
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
T179
V
M
Y
S
H
N
K
T
P
G
S
T
K
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
S149
D
D
D
S
P
G
V
S
H
S
G
P
V
K
A
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
L236
V
R
P
D
S
K
Q
L
L
L
S
P
G
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.3
97.5
N.A.
94.7
94.9
N.A.
N.A.
80
75
60.5
N.A.
51.3
50.9
24
58.9
Protein Similarity:
100
98.8
91.5
98.4
N.A.
96.9
96.9
N.A.
N.A.
89.9
89.1
76.7
N.A.
66.3
68.9
44.7
74.6
P-Site Identity:
100
100
6.6
93.3
N.A.
100
93.3
N.A.
N.A.
80
86.6
13.3
N.A.
20
46.6
20
53.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
93.3
N.A.
N.A.
80
93.3
26.6
N.A.
40
66.6
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
34
0
7
14
0
0
0
7
14
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
7
0
0
0
0
7
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
47
7
0
7
0
7
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
7
% H
% Ile:
0
0
0
7
0
14
0
0
0
7
7
7
0
0
0
% I
% Lys:
14
0
0
0
0
54
20
0
0
0
0
0
34
80
7
% K
% Leu:
0
47
7
0
0
0
7
7
7
7
0
7
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
14
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
14
0
0
20
67
7
0
14
0
0
14
% P
% Gln:
0
0
0
0
54
7
7
0
0
0
0
0
0
0
7
% Q
% Arg:
0
14
0
0
0
0
0
0
0
7
0
0
40
0
0
% R
% Ser:
7
0
0
74
20
14
0
7
0
14
80
47
0
7
14
% S
% Thr:
0
7
0
0
0
0
7
67
7
0
0
20
0
7
34
% T
% Val:
67
20
7
0
7
0
14
0
0
0
7
7
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
67
14
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _