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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20
All Species:
34.85
Human Site:
Y167
Identified Species:
54.76
UniProt:
Q12834
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12834
NP_001246.2
499
54723
Y167
S
S
R
K
T
C
R
Y
I
P
S
L
P
D
R
Chimpanzee
Pan troglodytes
XP_513374
499
54758
Y167
S
S
R
K
T
C
R
Y
I
P
S
L
P
D
R
Rhesus Macaque
Macaca mulatta
XP_001090604
457
50182
R140
I
L
D
A
P
E
I
R
N
D
Y
Y
L
N
L
Dog
Lupus familis
XP_539651
499
54777
Y167
S
T
R
K
T
C
R
Y
I
P
S
L
P
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
Y167
S
S
R
K
T
C
R
Y
I
P
S
L
P
D
R
Rat
Rattus norvegicus
Q62623
499
54810
Y167
S
S
R
K
A
C
R
Y
I
P
S
L
P
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006536
507
56149
Y174
S
S
R
K
H
G
R
Y
I
P
S
M
P
D
R
Frog
Xenopus laevis
NP_001079443
506
56086
Y174
S
S
K
K
T
G
R
Y
I
P
S
M
P
D
R
Zebra Danio
Brachydanio rerio
NP_998245
496
54922
Y168
V
S
V
K
K
S
R
Y
I
S
S
Y
P
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477501
526
57062
Y193
S
T
K
S
G
S
R
Y
I
P
T
T
S
E
R
Honey Bee
Apis mellifera
XP_624567
512
57052
Y180
S
I
K
T
S
T
R
Y
I
P
Q
N
P
D
R
Nematode Worm
Caenorhab. elegans
Q09373
507
56366
H160
S
V
K
K
S
T
R
H
V
K
E
T
A
T
K
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
H189
S
T
K
K
P
I
R
H
I
P
Q
Q
P
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
K159
G
P
V
K
A
P
R
K
V
P
R
S
P
Y
K
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
Q246
S
P
G
K
Q
F
R
Q
I
A
K
V
P
Y
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.3
97.5
N.A.
94.7
94.9
N.A.
N.A.
80
75
60.5
N.A.
51.3
50.9
24
58.9
Protein Similarity:
100
98.8
91.5
98.4
N.A.
96.9
96.9
N.A.
N.A.
89.9
89.1
76.7
N.A.
66.3
68.9
44.7
74.6
P-Site Identity:
100
100
0
93.3
N.A.
100
93.3
N.A.
N.A.
80
80
53.3
N.A.
40
53.3
20
46.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
93.3
N.A.
N.A.
86.6
93.3
60
N.A.
66.6
66.6
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
14
0
0
0
0
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
7
0
0
0
54
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
7
0
0
20
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
0
7
14
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
14
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
0
0
7
7
0
80
0
0
0
0
0
0
% I
% Lys:
0
0
34
80
7
0
0
7
0
7
7
0
0
0
14
% K
% Leu:
0
7
0
0
0
0
0
0
0
0
0
34
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
7
0
7
0
% N
% Pro:
0
14
0
0
14
7
0
0
0
74
0
0
80
0
0
% P
% Gln:
0
0
0
0
7
0
0
7
0
0
14
7
0
0
0
% Q
% Arg:
0
0
40
0
0
0
94
7
0
0
7
0
0
0
80
% R
% Ser:
80
47
0
7
14
14
0
0
0
7
54
7
7
0
0
% S
% Thr:
0
20
0
7
34
14
0
0
0
0
7
14
0
7
0
% T
% Val:
7
7
14
0
0
0
0
0
14
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
7
14
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _