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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20
All Species:
39.7
Human Site:
Y185
Identified Species:
62.38
UniProt:
Q12834
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12834
NP_001246.2
499
54723
Y185
A
P
E
I
R
N
D
Y
Y
L
N
L
V
D
W
Chimpanzee
Pan troglodytes
XP_513374
499
54758
Y185
A
P
E
I
R
N
D
Y
Y
L
N
L
V
D
W
Rhesus Macaque
Macaca mulatta
XP_001090604
457
50182
V158
S
S
G
N
V
L
A
V
A
L
D
N
S
V
Y
Dog
Lupus familis
XP_539651
499
54777
Y185
A
P
E
I
R
N
D
Y
Y
L
N
L
V
D
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
Y185
A
P
E
I
R
N
D
Y
Y
L
N
L
V
D
W
Rat
Rattus norvegicus
Q62623
499
54810
Y185
A
P
E
I
R
N
D
Y
Y
L
N
L
V
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006536
507
56149
Y192
A
P
E
I
R
N
D
Y
Y
L
N
L
I
D
W
Frog
Xenopus laevis
NP_001079443
506
56086
Y192
A
P
D
I
R
N
D
Y
Y
L
N
L
I
D
W
Zebra Danio
Brachydanio rerio
NP_998245
496
54922
F186
A
P
D
I
R
N
D
F
Y
L
N
L
M
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477501
526
57062
Y211
A
P
D
F
I
N
D
Y
Y
L
N
L
M
D
W
Honey Bee
Apis mellifera
XP_624567
512
57052
Y198
A
P
E
I
V
D
D
Y
Y
L
N
L
I
D
W
Nematode Worm
Caenorhab. elegans
Q09373
507
56366
L178
G
P
G
L
T
K
D
L
Y
S
R
H
L
D
W
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
Y207
A
P
D
M
L
D
D
Y
Y
L
N
L
L
D
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
F177
A
P
A
L
Q
D
D
F
Y
L
N
L
V
D
W
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
F264
A
P
S
L
A
D
D
F
Y
Y
S
L
I
D
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.3
97.5
N.A.
94.7
94.9
N.A.
N.A.
80
75
60.5
N.A.
51.3
50.9
24
58.9
Protein Similarity:
100
98.8
91.5
98.4
N.A.
96.9
96.9
N.A.
N.A.
89.9
89.1
76.7
N.A.
66.3
68.9
44.7
74.6
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
80
N.A.
73.3
80
33.3
66.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
86.6
93.3
46.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
87
0
7
0
7
0
7
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
27
0
0
27
94
0
0
0
7
0
0
94
0
% D
% Glu:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
7
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
60
7
0
0
0
0
0
0
0
27
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
20
7
7
0
7
0
87
0
87
14
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
14
0
0
% M
% Asn:
0
0
0
7
0
60
0
0
0
0
80
7
0
0
0
% N
% Pro:
0
94
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
54
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
7
7
7
0
0
0
0
0
0
7
7
0
7
0
0
% S
% Thr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
14
0
0
7
0
0
0
0
40
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
94
% W
% Tyr:
0
0
0
0
0
0
0
67
94
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _