KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20
All Species:
41.82
Human Site:
Y411
Identified Species:
65.71
UniProt:
Q12834
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12834
NP_001246.2
499
54723
Y411
S
I
L
W
S
P
H
Y
K
E
L
I
S
G
H
Chimpanzee
Pan troglodytes
XP_513374
499
54758
Y411
S
I
L
W
S
P
H
Y
K
E
L
I
S
G
H
Rhesus Macaque
Macaca mulatta
XP_001090604
457
50182
H376
Y
K
E
L
I
S
G
H
G
F
A
Q
N
Q
L
Dog
Lupus familis
XP_539651
499
54777
Y411
S
I
L
W
S
P
H
Y
K
E
L
I
S
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
Y411
S
I
L
W
S
P
H
Y
K
E
L
I
S
G
H
Rat
Rattus norvegicus
Q62623
499
54810
Y411
S
I
L
W
S
P
H
Y
K
E
L
I
S
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006536
507
56149
Y419
S
I
L
W
S
T
T
Y
K
E
F
I
S
G
H
Frog
Xenopus laevis
NP_001079443
506
56086
Y419
S
I
L
W
S
A
N
Y
K
E
L
I
S
G
H
Zebra Danio
Brachydanio rerio
NP_998245
496
54922
Y411
S
L
V
F
A
P
N
Y
K
E
L
V
S
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477501
526
57062
Y438
S
L
L
F
S
R
H
Y
K
E
L
I
S
A
H
Honey Bee
Apis mellifera
XP_624567
512
57052
Y425
S
L
L
W
S
T
T
Y
K
E
I
V
S
G
H
Nematode Worm
Caenorhab. elegans
Q09373
507
56366
N422
G
V
G
G
I
V
F
N
R
P
Y
S
E
M
L
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
H433
A
L
L
W
S
K
E
H
K
E
L
I
S
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
V398
N
L
A
W
S
K
N
V
N
E
L
V
S
T
H
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
T483
N
M
V
W
S
K
N
T
N
E
L
V
T
S
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.3
97.5
N.A.
94.7
94.9
N.A.
N.A.
80
75
60.5
N.A.
51.3
50.9
24
58.9
Protein Similarity:
100
98.8
91.5
98.4
N.A.
96.9
96.9
N.A.
N.A.
89.9
89.1
76.7
N.A.
66.3
68.9
44.7
74.6
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
80
86.6
60
N.A.
73.3
66.6
0
60
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
80
93.3
100
N.A.
86.6
86.6
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
7
7
0
0
0
0
7
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
0
7
0
0
87
0
0
7
0
0
% E
% Phe:
0
0
0
14
0
0
7
0
0
7
7
0
0
0
0
% F
% Gly:
7
0
7
7
0
0
7
0
7
0
0
0
0
60
0
% G
% His:
0
0
0
0
0
0
40
14
0
0
0
0
0
0
87
% H
% Ile:
0
47
0
0
14
0
0
0
0
0
7
60
0
0
0
% I
% Lys:
0
7
0
0
0
20
0
0
74
0
0
0
0
0
0
% K
% Leu:
0
34
67
7
0
0
0
0
0
0
74
0
0
0
14
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
14
0
0
0
0
0
27
7
14
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
40
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% Q
% Arg:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% R
% Ser:
67
0
0
0
80
7
0
0
0
0
0
7
80
7
0
% S
% Thr:
0
0
0
0
0
14
14
7
0
0
0
0
7
7
0
% T
% Val:
0
7
14
0
0
7
0
7
0
0
0
27
0
0
0
% V
% Trp:
0
0
0
74
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
67
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _