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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU4F2 All Species: 18.18
Human Site: S157 Identified Species: 30.77
UniProt: Q12837 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12837 NP_004566.2 409 43087 S157 C T S A A S S S S V P I S H P
Chimpanzee Pan troglodytes XP_526699 406 42885 S154 C T S A A S S S S V P I S H P
Rhesus Macaque Macaca mulatta XP_001098227 408 43070 S156 C T S A A S S S S V P I S H P
Dog Lupus familis XP_539754 322 35359 M118 P G L A L G A M A G P D G A V
Cat Felis silvestris
Mouse Mus musculus Q63934 411 43154 S159 C T S A A S S S S V P I S H P
Rat Rattus norvegicus P20266 128 14214
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511297 1610 174405 S300 C T S A A S S S S V P I S H P
Chicken Gallus gallus Q91998 341 37755 P138 P L G G V P G P D V G S T P S
Frog Xenopus laevis P70030 385 41967 G157 G M I N P G S G Q G M H H H G
Zebra Danio Brachydanio rerio Q90435 331 36531 G127 S L S V S G M G A P P D P S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24350 396 43685 G153 L D M L D P T G S M T T L A P
Honey Bee Apis mellifera XP_394134 364 38864 G156 H G P S V Y G G M N G M M G H
Nematode Worm Caenorhab. elegans P13528 467 52296 I191 D T S A A T N I Y Q G L P S S
Sea Urchin Strong. purpuratus XP_786727 349 37858 Q146 G P G L S D V Q S A A A A A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98 77.7 N.A. 97.5 29.5 N.A. 23.3 60.3 29.5 61.3 N.A. 43.5 44.9 32.1 48.4
Protein Similarity: 100 99 98.2 77.7 N.A. 97.5 30.3 N.A. 24.2 68.6 42.5 68.6 N.A. 54 55.5 43.6 56.2
P-Site Identity: 100 100 100 13.3 N.A. 100 0 N.A. 100 6.6 13.3 13.3 N.A. 13.3 0 26.6 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 100 0 N.A. 100 13.3 13.3 26.6 N.A. 26.6 13.3 46.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 50 43 0 8 0 15 8 8 8 8 22 8 % A
% Cys: 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 8 8 0 0 8 0 0 15 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 15 15 8 0 22 15 29 0 15 22 0 8 8 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 8 8 43 8 % H
% Ile: 0 0 8 0 0 0 0 8 0 0 0 36 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 15 8 15 8 0 0 0 0 0 0 8 8 0 0 % L
% Met: 0 8 8 0 0 0 8 8 8 8 8 8 8 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 0 % N
% Pro: 15 8 8 0 8 15 0 8 0 8 50 0 15 8 43 % P
% Gln: 0 0 0 0 0 0 0 8 8 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 50 8 15 36 43 36 50 0 0 8 36 15 15 % S
% Thr: 0 43 0 0 0 8 8 0 0 0 8 8 8 0 0 % T
% Val: 0 0 0 8 15 0 8 0 0 43 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _