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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU4F2 All Species: 18.79
Human Site: S33 Identified Species: 31.79
UniProt: Q12837 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12837 NP_004566.2 409 43087 S33 Y S A L H S T S P G S S A P I
Chimpanzee Pan troglodytes XP_526699 406 42885 S33 Y S A L H S T S P G S S A P T
Rhesus Macaque Macaca mulatta XP_001098227 408 43070 S33 Y S A L H S T S P G S T A P T
Dog Lupus familis XP_539754 322 35359
Cat Felis silvestris
Mouse Mus musculus Q63934 411 43154 S33 Y S A L H S A S P G S S A P A
Rat Rattus norvegicus P20266 128 14214
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511297 1610 174405 S171 Y S A L H T A S P C T S A P A
Chicken Gallus gallus Q91998 341 37755 E18 S M H P I L H E P K Y P H L H
Frog Xenopus laevis P70030 385 41967 T37 Q S Y R D A Q T L V Q S D Y T
Zebra Danio Brachydanio rerio Q90435 331 36531
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24350 396 43685 Q33 P S Y R S S E Q M R R C M P N
Honey Bee Apis mellifera XP_394134 364 38864 P36 R A A P D P M P P P P R R C M
Nematode Worm Caenorhab. elegans P13528 467 52296 S50 F N P L L R P S K I S R G S E
Sea Urchin Strong. purpuratus XP_786727 349 37858 R26 P K Y S P L H R H H D R G L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98 77.7 N.A. 97.5 29.5 N.A. 23.3 60.3 29.5 61.3 N.A. 43.5 44.9 32.1 48.4
Protein Similarity: 100 99 98.2 77.7 N.A. 97.5 30.3 N.A. 24.2 68.6 42.5 68.6 N.A. 54 55.5 43.6 56.2
P-Site Identity: 100 93.3 86.6 0 N.A. 86.6 0 N.A. 66.6 6.6 13.3 0 N.A. 20 13.3 20 0
P-Site Similarity: 100 93.3 93.3 0 N.A. 86.6 0 N.A. 80 6.6 26.6 0 N.A. 20 26.6 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 43 0 0 8 15 0 0 0 0 0 36 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % C
% Asp: 0 0 0 0 15 0 0 0 0 0 8 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 15 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 29 0 0 15 0 0 % G
% His: 0 0 8 0 36 0 15 0 8 8 0 0 8 0 8 % H
% Ile: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 8 % I
% Lys: 0 8 0 0 0 0 0 0 8 8 0 0 0 0 0 % K
% Leu: 0 0 0 43 8 15 0 0 8 0 0 0 0 15 0 % L
% Met: 0 8 0 0 0 0 8 0 8 0 0 0 8 0 8 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 15 0 8 15 8 8 8 8 50 8 8 8 0 43 0 % P
% Gln: 8 0 0 0 0 0 8 8 0 0 8 0 0 0 0 % Q
% Arg: 8 0 0 15 0 8 0 8 0 8 8 22 8 0 0 % R
% Ser: 8 50 0 8 8 36 0 43 0 0 36 36 0 8 0 % S
% Thr: 0 0 0 0 0 8 22 8 0 0 8 8 0 0 22 % T
% Val: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 36 0 22 0 0 0 0 0 0 0 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _