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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU4F2
All Species:
18.18
Human Site:
S372
Identified Species:
30.77
UniProt:
Q12837
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12837
NP_004566.2
409
43087
S372
A
I
Q
P
R
P
S
S
E
K
I
A
A
I
A
Chimpanzee
Pan troglodytes
XP_526699
406
42885
S369
A
I
Q
P
R
P
S
S
E
K
I
A
A
I
A
Rhesus Macaque
Macaca mulatta
XP_001098227
408
43070
S371
A
I
Q
P
R
P
S
S
E
K
I
A
A
I
A
Dog
Lupus familis
XP_539754
322
35359
R303
D
L
K
K
N
V
V
R
V
W
F
C
N
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q63934
411
43154
S374
A
I
Q
P
R
P
S
S
E
K
I
A
A
I
A
Rat
Rattus norvegicus
P20266
128
14214
A110
P
S
S
E
K
I
A
A
I
A
E
K
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511297
1610
174405
S515
A
I
Q
P
R
P
S
S
E
K
I
A
A
I
A
Chicken
Gallus gallus
Q91998
341
37755
V323
L
K
K
N
V
V
R
V
W
F
C
N
Q
R
Q
Frog
Xenopus laevis
P70030
385
41967
A364
P
G
G
T
I
P
G
A
E
D
V
Y
G
A
S
Zebra Danio
Brachydanio rerio
Q90435
331
36531
R312
D
L
K
K
N
V
V
R
V
W
F
C
N
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24350
396
43685
G347
A
V
Q
P
R
P
S
G
E
K
I
A
A
I
A
Honey Bee
Apis mellifera
XP_394134
364
38864
V343
K
L
D
L
K
K
N
V
V
R
V
W
F
C
N
Nematode Worm
Caenorhab. elegans
P13528
467
52296
G390
K
Q
Q
P
R
P
S
G
E
R
I
A
S
I
A
Sea Urchin
Strong. purpuratus
XP_786727
349
37858
W331
K
K
N
V
V
R
V
W
F
C
N
Q
R
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98
77.7
N.A.
97.5
29.5
N.A.
23.3
60.3
29.5
61.3
N.A.
43.5
44.9
32.1
48.4
Protein Similarity:
100
99
98.2
77.7
N.A.
97.5
30.3
N.A.
24.2
68.6
42.5
68.6
N.A.
54
55.5
43.6
56.2
P-Site Identity:
100
100
100
0
N.A.
100
0
N.A.
100
0
13.3
0
N.A.
86.6
0
66.6
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
20
N.A.
100
6.6
33.3
13.3
N.A.
93.3
33.3
80
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
0
0
0
0
8
15
0
8
0
50
43
8
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
15
0
8
0
% C
% Asp:
15
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% D
% Glu:
0
0
0
8
0
0
0
0
58
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
15
0
8
0
0
% F
% Gly:
0
8
8
0
0
0
8
15
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
36
0
0
8
8
0
0
8
0
50
0
0
50
0
% I
% Lys:
22
15
22
15
15
8
0
0
0
43
0
8
0
0
8
% K
% Leu:
8
22
0
8
0
0
0
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
15
0
8
0
0
0
8
8
15
0
8
% N
% Pro:
15
0
0
50
0
58
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
50
0
0
0
0
0
0
0
0
8
8
22
8
% Q
% Arg:
0
0
0
0
50
8
8
15
0
15
0
0
8
8
15
% R
% Ser:
0
8
8
0
0
0
50
36
0
0
0
0
8
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
8
15
22
22
15
22
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
8
15
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _