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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU4F2
All Species:
20.3
Human Site:
S46
Identified Species:
34.36
UniProt:
Q12837
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12837
NP_004566.2
409
43087
S46
P
I
A
P
S
A
S
S
P
S
S
S
S
N
A
Chimpanzee
Pan troglodytes
XP_526699
406
42885
S46
P
T
A
P
S
A
S
S
P
S
S
S
S
N
A
Rhesus Macaque
Macaca mulatta
XP_001098227
408
43070
S46
P
T
A
P
S
A
S
S
P
S
S
S
S
N
A
Dog
Lupus familis
XP_539754
322
35359
N11
F
Y
L
Q
L
Q
S
N
I
F
G
G
L
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q63934
411
43154
S46
P
A
A
P
S
A
S
S
P
S
S
S
S
N
A
Rat
Rattus norvegicus
P20266
128
14214
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511297
1610
174405
S184
P
A
A
P
S
S
S
S
P
S
S
S
S
S
P
Chicken
Gallus gallus
Q91998
341
37755
I31
L
H
T
S
S
E
A
I
R
R
A
C
L
P
A
Frog
Xenopus laevis
P70030
385
41967
H50
Y
T
L
Q
S
N
G
H
P
L
S
H
A
H
Q
Zebra Danio
Brachydanio rerio
Q90435
331
36531
S20
H
P
A
L
H
P
S
S
E
G
M
R
R
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24350
396
43685
S46
P
N
P
S
I
H
I
S
S
S
C
D
S
L
E
Honey Bee
Apis mellifera
XP_394134
364
38864
D49
C
M
P
N
P
T
G
D
L
F
G
G
L
N
S
Nematode Worm
Caenorhab. elegans
P13528
467
52296
S63
S
E
N
G
A
C
T
S
H
S
T
L
Q
R
T
Sea Urchin
Strong. purpuratus
XP_786727
349
37858
C39
L
E
M
T
R
R
H
C
M
N
G
P
G
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98
77.7
N.A.
97.5
29.5
N.A.
23.3
60.3
29.5
61.3
N.A.
43.5
44.9
32.1
48.4
Protein Similarity:
100
99
98.2
77.7
N.A.
97.5
30.3
N.A.
24.2
68.6
42.5
68.6
N.A.
54
55.5
43.6
56.2
P-Site Identity:
100
93.3
93.3
6.6
N.A.
93.3
0
N.A.
73.3
13.3
20
20
N.A.
26.6
6.6
13.3
6.6
P-Site Similarity:
100
93.3
93.3
20
N.A.
93.3
0
N.A.
86.6
26.6
33.3
20
N.A.
26.6
20
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
43
0
8
29
8
0
0
0
8
0
8
0
36
% A
% Cys:
8
0
0
0
0
8
0
8
0
0
8
8
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% D
% Glu:
0
15
0
0
0
8
0
0
8
0
0
0
0
0
15
% E
% Phe:
8
0
0
0
0
0
0
0
0
15
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
15
0
0
8
22
15
8
0
0
% G
% His:
8
8
0
0
8
8
8
8
8
0
0
8
0
8
0
% H
% Ile:
0
8
0
0
8
0
8
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
0
15
8
8
0
0
0
8
8
0
8
22
8
0
% L
% Met:
0
8
8
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
8
8
8
0
8
0
8
0
8
0
0
0
43
0
% N
% Pro:
43
8
15
36
8
8
0
0
43
0
0
8
0
8
8
% P
% Gln:
0
0
0
15
0
8
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
0
8
8
0
0
8
8
0
8
8
8
0
% R
% Ser:
8
0
0
15
50
8
50
58
8
50
43
36
43
8
8
% S
% Thr:
0
22
8
8
0
8
8
0
0
0
8
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _