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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU4F2
All Species:
9.09
Human Site:
S74
Identified Species:
15.38
UniProt:
Q12837
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12837
NP_004566.2
409
43087
S74
G
G
R
S
S
S
S
S
S
S
G
S
S
G
G
Chimpanzee
Pan troglodytes
XP_526699
406
42885
S71
G
G
R
S
S
S
S
S
S
S
G
S
S
G
G
Rhesus Macaque
Macaca mulatta
XP_001098227
408
43070
S73
R
N
S
S
S
S
S
S
G
S
S
G
S
G
G
Dog
Lupus familis
XP_539754
322
35359
Q35
A
A
V
D
I
V
S
Q
S
K
S
H
H
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q63934
411
43154
G76
S
S
S
S
S
S
S
G
S
G
G
S
G
G
G
Rat
Rattus norvegicus
P20266
128
14214
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511297
1610
174405
G217
S
S
S
S
S
G
G
G
S
S
S
S
S
G
G
Chicken
Gallus gallus
Q91998
341
37755
R55
G
F
D
E
T
L
L
R
G
A
E
A
L
A
A
Frog
Xenopus laevis
P70030
385
41967
P74
G
A
P
W
A
T
S
P
L
G
Q
Q
D
I
K
Zebra Danio
Brachydanio rerio
Q90435
331
36531
S44
I
F
S
G
F
D
E
S
L
L
A
R
A
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24350
396
43685
R70
L
C
N
S
W
S
A
R
Q
N
G
D
I
F
A
Honey Bee
Apis mellifera
XP_394134
364
38864
L73
A
E
A
L
A
A
D
L
G
K
H
N
A
G
T
Nematode Worm
Caenorhab. elegans
P13528
467
52296
S108
S
F
K
V
P
L
F
S
T
D
M
Q
N
T
A
Sea Urchin
Strong. purpuratus
XP_786727
349
37858
A63
L
A
R
A
E
A
L
A
A
V
D
V
M
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98
77.7
N.A.
97.5
29.5
N.A.
23.3
60.3
29.5
61.3
N.A.
43.5
44.9
32.1
48.4
Protein Similarity:
100
99
98.2
77.7
N.A.
97.5
30.3
N.A.
24.2
68.6
42.5
68.6
N.A.
54
55.5
43.6
56.2
P-Site Identity:
100
100
60
13.3
N.A.
60
0
N.A.
53.3
6.6
13.3
6.6
N.A.
20
6.6
6.6
6.6
P-Site Similarity:
100
100
60
13.3
N.A.
60
0
N.A.
53.3
26.6
26.6
13.3
N.A.
33.3
33.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
22
8
8
15
15
8
8
8
8
8
8
15
8
29
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
8
0
0
8
8
8
8
0
0
% D
% Glu:
0
8
0
8
8
0
8
0
0
0
8
0
0
8
0
% E
% Phe:
0
22
0
0
8
0
8
0
0
0
0
0
0
8
0
% F
% Gly:
29
15
0
8
0
8
8
15
22
15
29
8
8
43
36
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
8
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
15
0
0
0
0
8
% K
% Leu:
15
0
0
8
0
15
15
8
15
8
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
8
0
8
8
0
0
% N
% Pro:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
8
15
0
0
0
% Q
% Arg:
8
0
22
0
0
0
0
15
0
0
0
8
0
0
0
% R
% Ser:
22
15
29
43
36
36
43
36
36
29
22
29
29
8
8
% S
% Thr:
0
0
0
0
8
8
0
0
8
0
0
0
0
8
8
% T
% Val:
0
0
8
8
0
8
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _