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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
21.82
Human Site:
S368
Identified Species:
34.29
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
S368
A
K
L
E
A
E
L
S
R
W
R
N
G
E
N
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
S364
A
K
L
E
A
E
L
S
R
W
R
N
G
E
N
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
G260
F
T
K
T
R
A
A
G
Y
C
Q
L
S
F
E
Dog
Lupus familis
XP_849802
1032
117317
S368
A
K
L
E
A
E
L
S
R
W
R
N
G
E
N
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
S368
A
K
L
E
A
E
L
S
R
W
R
N
G
E
N
Rat
Rattus norvegicus
Q6QLM7
1027
116897
S368
A
K
L
E
A
E
L
S
R
W
R
N
G
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
I358
N
K
T
L
R
N
T
I
Q
W
L
E
N
E
L
Chicken
Gallus gallus
Q90640
1225
138905
I379
G
G
T
L
P
V
S
I
N
S
M
A
P
S
E
Frog
Xenopus laevis
Q91784
1226
138905
N378
G
G
T
L
P
V
L
N
S
M
E
P
S
E
N
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
A251
E
G
A
V
L
D
E
A
K
N
I
N
K
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
A374
E
K
L
E
I
E
L
A
R
W
R
A
G
E
T
Honey Bee
Apis mellifera
XP_395236
988
112484
S378
E
K
L
E
A
E
L
S
R
W
R
Q
G
E
T
Nematode Worm
Caenorhab. elegans
P34540
815
91875
V215
H
S
V
F
L
I
T
V
K
Q
E
H
Q
T
T
Sea Urchin
Strong. purpuratus
P35978
1031
117504
Q366
L
I
L
E
N
E
L
Q
R
W
R
A
G
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
K328
L
R
F
G
M
R
A
K
S
I
K
N
K
A
K
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
20
0
20
6.6
N.A.
66.6
80
0
60
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
26.6
0
26.6
26.6
N.A.
73.3
80
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
7
0
40
7
14
14
0
0
0
20
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
0
54
0
54
7
0
0
0
14
7
0
67
14
% E
% Phe:
7
0
7
7
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
14
20
0
7
0
0
0
7
0
0
0
0
54
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
7
7
0
14
0
7
7
0
0
0
0
% I
% Lys:
0
54
7
0
0
0
0
7
14
0
7
0
14
0
7
% K
% Leu:
14
0
54
20
14
0
60
0
0
0
7
7
0
0
14
% L
% Met:
0
0
0
0
7
0
0
0
0
7
7
0
0
0
0
% M
% Asn:
7
0
0
0
7
7
0
7
7
7
0
47
7
0
40
% N
% Pro:
0
0
0
0
14
0
0
0
0
0
0
7
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
7
7
7
7
7
0
0
% Q
% Arg:
0
7
0
0
14
7
0
0
54
0
54
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
7
40
14
7
0
0
14
14
7
% S
% Thr:
0
7
20
7
0
0
14
0
0
0
0
0
0
7
20
% T
% Val:
0
0
7
7
0
14
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _