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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
8.48
Human Site:
S754
Identified Species:
13.33
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
S754
A
D
Y
E
K
L
K
S
E
E
H
E
K
S
T
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
S750
A
D
Y
K
K
L
K
S
E
E
H
E
K
S
T
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
A605
D
A
E
E
M
K
K
A
L
E
Q
Q
M
E
S
Dog
Lupus familis
XP_849802
1032
117317
N754
A
D
Y
E
K
L
K
N
E
E
H
E
K
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
N754
A
D
Y
E
R
L
K
N
E
E
N
E
K
S
A
Rat
Rattus norvegicus
Q6QLM7
1027
116897
N754
A
D
Y
E
R
L
K
N
E
E
N
E
K
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
N707
A
V
E
Q
Q
I
Q
N
H
R
E
T
H
Q
K
Chicken
Gallus gallus
Q90640
1225
138905
R768
V
S
T
E
E
A
R
R
H
L
A
D
L
L
E
Frog
Xenopus laevis
Q91784
1226
138905
T826
K
Q
I
E
S
L
E
T
E
M
E
L
R
S
A
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
R596
D
E
E
F
T
V
A
R
L
Y
I
S
K
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
S720
Q
R
A
E
E
L
R
S
M
F
D
S
Q
M
D
Honey Bee
Apis mellifera
XP_395236
988
112484
D731
E
Q
M
D
Q
L
R
D
A
H
Q
K
Q
V
A
Nematode Worm
Caenorhab. elegans
P34540
815
91875
H560
E
C
G
P
K
I
R
H
F
K
E
G
I
Y
N
Sea Urchin
Strong. purpuratus
P35978
1031
117504
I751
L
D
Y
E
K
L
K
I
E
E
A
E
K
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
L673
D
K
E
E
V
K
A
L
L
A
K
S
L
S
D
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
93.3
20
86.6
N.A.
73.3
73.3
N.A.
6.6
6.6
26.6
6.6
N.A.
20
6.6
6.6
66.6
P-Site Similarity:
100
100
40
100
N.A.
93.3
93.3
N.A.
40
26.6
46.6
20
N.A.
40
40
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
7
7
0
0
7
14
7
7
7
14
0
0
7
34
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
40
0
7
0
0
0
7
0
0
7
7
0
0
14
% D
% Glu:
14
7
27
67
14
0
7
0
47
47
20
40
0
7
7
% E
% Phe:
0
0
0
7
0
0
0
0
7
7
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
14
7
20
0
7
0
0
% H
% Ile:
0
0
7
0
0
14
0
7
0
0
7
0
7
0
0
% I
% Lys:
7
7
0
7
34
14
47
0
0
7
7
7
47
0
14
% K
% Leu:
7
0
0
0
0
60
0
7
20
7
0
7
14
7
0
% L
% Met:
0
0
7
0
7
0
0
0
7
7
0
0
7
14
0
% M
% Asn:
0
0
0
0
0
0
0
27
0
0
14
0
0
0
7
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
14
0
7
14
0
7
0
0
0
14
7
14
7
0
% Q
% Arg:
0
7
0
0
14
0
27
14
0
7
0
0
7
0
0
% R
% Ser:
0
7
0
0
7
0
0
20
0
0
0
20
0
47
14
% S
% Thr:
0
0
7
0
7
0
0
7
0
0
0
7
0
0
14
% T
% Val:
7
7
0
0
7
7
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
40
0
0
0
0
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _