KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
20.91
Human Site:
S825
Identified Species:
32.86
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
S825
E
D
S
G
G
I
H
S
Q
K
Q
K
I
S
F
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
S821
E
D
S
G
G
I
H
S
Q
K
Q
K
I
S
F
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
L676
K
L
E
K
L
L
L
L
N
D
K
R
E
Q
A
Dog
Lupus familis
XP_849802
1032
117317
S825
E
D
S
G
G
I
H
S
Q
K
Q
K
I
S
F
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
S825
E
D
S
G
G
I
H
S
Q
K
Q
K
I
S
F
Rat
Rattus norvegicus
Q6QLM7
1027
116897
S825
E
D
S
G
G
I
H
S
Q
K
Q
K
I
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
A778
M
Q
D
R
R
E
Q
A
R
Q
D
L
K
G
L
Chicken
Gallus gallus
Q90640
1225
138905
A839
E
L
R
S
A
Q
I
A
D
L
Q
Q
K
L
L
Frog
Xenopus laevis
Q91784
1226
138905
V897
V
K
Q
N
R
A
H
V
A
D
L
Q
K
N
I
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
E667
Q
K
K
R
Q
L
E
E
D
V
D
S
L
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
L791
S
E
L
Q
N
I
I
L
T
N
E
R
R
E
Q
Honey Bee
Apis mellifera
XP_395236
988
112484
D802
R
R
E
Q
A
R
K
D
L
K
G
L
E
E
T
Nematode Worm
Caenorhab. elegans
P34540
815
91875
S631
A
D
V
A
R
V
E
S
G
Q
D
A
G
R
M
Sea Urchin
Strong. purpuratus
P35978
1031
117504
S822
R
D
D
D
S
G
G
S
Q
A
Q
K
Q
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
K744
A
E
F
D
V
M
K
K
S
L
M
R
D
L
Q
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
13.3
6.6
0
N.A.
6.6
6.6
13.3
33.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
20
26.6
20
26.6
N.A.
26.6
6.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
7
14
7
0
14
7
7
0
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
14
14
0
0
0
7
14
14
20
0
7
0
0
% D
% Glu:
40
14
14
0
0
7
14
7
0
0
7
0
14
14
7
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
34
% F
% Gly:
0
0
0
34
34
7
7
0
7
0
7
0
7
7
0
% G
% His:
0
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
40
14
0
0
0
0
0
34
0
14
% I
% Lys:
7
14
7
7
0
0
14
7
0
40
7
40
20
7
0
% K
% Leu:
0
14
7
0
7
14
7
14
7
14
7
14
7
14
14
% L
% Met:
7
0
0
0
0
7
0
0
0
0
7
0
0
0
7
% M
% Asn:
0
0
0
7
7
0
0
0
7
7
0
0
0
14
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
7
14
7
7
7
0
40
14
47
14
7
7
14
% Q
% Arg:
14
7
7
14
20
7
0
0
7
0
0
20
7
7
0
% R
% Ser:
7
0
34
7
7
0
0
47
7
0
0
7
0
34
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% T
% Val:
7
0
7
0
7
7
0
7
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _