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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5A All Species: 11.21
Human Site: S908 Identified Species: 17.62
UniProt: Q12840 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12840 NP_004975.2 1032 117378 S908 K E A V R Y K S S G K R G H S
Chimpanzee Pan troglodytes XP_509167 1028 117090 S904 K E A V R Y K S S G K R G H S
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 I737 S A A Q K Q K I S F L E N N L
Dog Lupus familis XP_849802 1032 117317 S908 K E A V R Y K S S G K R G H S
Cat Felis silvestris
Mouse Mus musculus P33175 1027 117000 A903 E V D R I K E A V R Y K S S G
Rat Rattus norvegicus Q6QLM7 1027 116897 A903 E V D R I K E A V R Y K S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 L842 L E N N L E Q L T K V H K Q L
Chicken Gallus gallus Q90640 1225 138905 A1004 K M L L V Q V A S G Q K L R R
Frog Xenopus laevis Q91784 1226 138905 A1007 K L A L L H V A S G K K L H N
Zebra Danio Brachydanio rerio XP_691912 851 97123 T728 S L R D E L E T K E K L I T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 Q852 G G S L A Q K Q K I S F L E N
Honey Bee Apis mellifera XP_395236 988 112484 T865 E N N L D Q L T K V H K Q L V
Nematode Worm Caenorhab. elegans P34540 815 91875 L692 D T E G E D S L S G P A Q K Q
Sea Urchin Strong. purpuratus P35978 1031 117504 N907 R E A V R Q R N F A K R G S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 V805 T Q V Q R Q L V E Q N S A L K
Conservation
Percent
Protein Identity: 100 97.6 60 99 N.A. 97.6 96.8 N.A. 66.6 26.2 26.1 59 N.A. 56.4 60 41.7 59
Protein Similarity: 100 97.9 70.8 99.7 N.A. 99 98.6 N.A. 80 44.3 45.9 70.6 N.A. 72.1 75.2 56.4 74.7
P-Site Identity: 100 100 20 100 N.A. 0 0 N.A. 6.6 20 40 6.6 N.A. 6.6 0 13.3 53.3
P-Site Similarity: 100 100 33.3 100 N.A. 26.6 26.6 N.A. 20 46.6 73.3 20 N.A. 26.6 26.6 13.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 51.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 40 0 7 0 0 27 0 7 0 7 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 14 7 7 7 0 0 0 0 0 0 0 0 7 % D
% Glu: 20 34 7 0 14 7 20 0 7 7 0 7 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 7 0 7 0 0 0 % F
% Gly: 7 7 0 7 0 0 0 0 0 40 0 0 27 0 14 % G
% His: 0 0 0 0 0 7 0 0 0 0 7 7 0 27 0 % H
% Ile: 0 0 0 0 14 0 0 7 0 7 0 0 7 0 0 % I
% Lys: 34 0 0 0 7 14 34 0 20 7 40 34 7 7 7 % K
% Leu: 7 14 7 27 14 7 14 14 0 0 7 7 20 14 14 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 14 7 0 0 0 7 0 0 7 0 7 7 14 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 7 0 14 0 40 7 7 0 7 7 0 14 7 7 % Q
% Arg: 7 0 7 14 34 0 7 0 0 14 0 27 0 7 7 % R
% Ser: 14 0 7 0 0 0 7 20 47 0 7 7 14 20 27 % S
% Thr: 7 7 0 0 0 0 0 14 7 0 0 0 0 7 0 % T
% Val: 0 14 7 27 7 0 14 7 14 7 7 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 20 0 0 0 0 14 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _