Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5A All Species: 8.48
Human Site: S967 Identified Species: 13.33
UniProt: Q12840 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12840 NP_004975.2 1032 117378 S967 Q A T P S S T S D M Y F A N S
Chimpanzee Pan troglodytes XP_509167 1028 117090 S963 Q A T P S S T S D M Y F A N S
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 D796 A K E N A M R D R K R Y Q Q E
Dog Lupus familis XP_849802 1032 117317 S967 Q G A P S S T S D M Y F A N S
Cat Felis silvestris
Mouse Mus musculus P33175 1027 117000 A962 Q N L H L Q A A P S S T S D M
Rat Rattus norvegicus Q6QLM7 1027 116897 A962 Q N L H L Q A A P S S T S D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 R901 R Y Q Q E V D R I K E A V R S
Chicken Gallus gallus Q90640 1225 138905 E1063 D S E E S G E E E D A E W V P
Frog Xenopus laevis Q91784 1226 138905 K1066 S E E E S D D K N W E P G N N
Zebra Danio Brachydanio rerio XP_691912 851 97123 G787 Q A R Q D L K G L E E T V A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 M911 K E A K E G A M R D R K R Y Q
Honey Bee Apis mellifera XP_395236 988 112484 I924 Y Q Y E V D R I K E A V R Q K
Nematode Worm Caenorhab. elegans P34540 815 91875 R751 K I L E T A L R D S K Q R S Q
Sea Urchin Strong. purpuratus P35978 1031 117504 N966 S P E P I S H N N S F E K S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 A864 V K D R L E A A K A G S T R G
Conservation
Percent
Protein Identity: 100 97.6 60 99 N.A. 97.6 96.8 N.A. 66.6 26.2 26.1 59 N.A. 56.4 60 41.7 59
Protein Similarity: 100 97.9 70.8 99.7 N.A. 99 98.6 N.A. 80 44.3 45.9 70.6 N.A. 72.1 75.2 56.4 74.7
P-Site Identity: 100 100 0 86.6 N.A. 6.6 6.6 N.A. 6.6 6.6 13.3 13.3 N.A. 0 0 6.6 13.3
P-Site Similarity: 100 100 13.3 86.6 N.A. 26.6 26.6 N.A. 13.3 20 26.6 13.3 N.A. 6.6 0 33.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 51.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 14 0 7 7 27 20 0 7 14 7 20 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 7 14 14 7 27 14 0 0 0 14 0 % D
% Glu: 0 14 27 27 14 7 7 7 7 14 20 14 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 20 0 0 0 % F
% Gly: 0 7 0 0 0 14 0 7 0 0 7 0 7 0 7 % G
% His: 0 0 0 14 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 7 0 0 7 7 0 0 0 0 0 0 % I
% Lys: 14 14 0 7 0 0 7 7 14 14 7 7 7 0 14 % K
% Leu: 0 0 20 0 20 7 7 0 7 0 0 0 0 0 7 % L
% Met: 0 0 0 0 0 7 0 7 0 20 0 0 0 0 7 % M
% Asn: 0 14 0 7 0 0 0 7 14 0 0 0 0 27 7 % N
% Pro: 0 7 0 27 0 0 0 0 14 0 0 7 0 0 7 % P
% Gln: 40 7 7 14 0 14 0 0 0 0 0 7 7 14 14 % Q
% Arg: 7 0 7 7 0 0 14 14 14 0 14 0 20 14 0 % R
% Ser: 14 7 0 0 34 27 0 20 0 27 14 7 14 14 27 % S
% Thr: 0 0 14 0 7 0 20 0 0 0 0 20 7 0 0 % T
% Val: 7 0 0 0 7 7 0 0 0 0 0 7 14 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % W
% Tyr: 7 7 7 0 0 0 0 0 0 0 20 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _