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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
22.73
Human Site:
T220
Identified Species:
35.71
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
T220
I
K
Q
E
N
M
E
T
E
Q
K
L
S
G
K
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
T216
I
K
Q
E
N
M
E
T
E
Q
K
L
S
G
K
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
L113
S
R
S
H
S
I
F
L
I
N
I
K
Q
E
N
Dog
Lupus familis
XP_849802
1032
117317
T220
I
K
Q
E
N
M
E
T
E
Q
K
L
S
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
T220
I
K
Q
E
N
V
E
T
E
Q
K
L
S
G
K
Rat
Rattus norvegicus
Q6QLM7
1027
116897
T220
I
K
Q
E
N
I
E
T
E
Q
K
L
S
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
F208
S
S
R
S
H
S
I
F
L
I
N
V
K
Q
E
Chicken
Gallus gallus
Q90640
1225
138905
D228
I
D
Q
K
K
K
N
D
K
N
S
S
F
H
S
Frog
Xenopus laevis
Q91784
1226
138905
K228
E
Q
R
K
E
G
D
K
N
N
S
F
R
S
K
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
G104
G
N
L
H
D
T
D
G
M
G
I
I
P
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
N226
V
K
Q
E
N
L
E
N
Q
K
K
L
S
G
K
Honey Bee
Apis mellifera
XP_395236
988
112484
N230
V
K
Q
E
N
L
E
N
Q
K
K
L
S
G
K
Nematode Worm
Caenorhab. elegans
P34540
815
91875
A68
Q
E
Q
V
Y
K
G
A
A
Y
H
I
V
Q
D
Sea Urchin
Strong. purpuratus
P35978
1031
117504
T218
V
K
Q
E
N
M
E
T
K
K
K
L
S
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
Q181
E
I
Y
V
S
S
V
Q
E
V
Y
E
V
M
R
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
0
13.3
6.6
0
N.A.
66.6
66.6
6.6
80
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
26.6
26.6
33.3
20
N.A.
93.3
93.3
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
0
14
7
0
0
0
0
0
0
7
% D
% Glu:
14
7
0
54
7
0
54
0
40
0
0
7
0
7
7
% E
% Phe:
0
0
0
0
0
0
7
7
0
0
0
7
7
0
0
% F
% Gly:
7
0
0
0
0
7
7
7
0
7
0
0
0
54
0
% G
% His:
0
0
0
14
7
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
40
7
0
0
0
14
7
0
7
7
14
14
0
0
7
% I
% Lys:
0
54
0
14
7
14
0
7
14
20
54
7
7
0
60
% K
% Leu:
0
0
7
0
0
14
0
7
7
0
0
54
0
0
0
% L
% Met:
0
0
0
0
0
27
0
0
7
0
0
0
0
7
0
% M
% Asn:
0
7
0
0
54
0
7
14
7
20
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
7
7
67
0
0
0
0
7
14
34
0
0
7
14
0
% Q
% Arg:
0
7
14
0
0
0
0
0
0
0
0
0
7
7
7
% R
% Ser:
14
7
7
7
14
14
0
0
0
0
14
7
54
7
7
% S
% Thr:
0
0
0
0
0
7
0
40
0
0
0
0
0
0
0
% T
% Val:
20
0
0
14
0
7
7
0
0
7
0
7
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _