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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5A All Species: 20
Human Site: T379 Identified Species: 31.43
UniProt: Q12840 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12840 NP_004975.2 1032 117378 T379 N G E N V P E T E R L A G E E
Chimpanzee Pan troglodytes XP_509167 1028 117090 T375 N G E N V P E T E R L A G E E
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 T271 L S F E T Q H T H W K K G E A
Dog Lupus familis XP_849802 1032 117317 T379 N G E N V P E T E R L A G D D
Cat Felis silvestris
Mouse Mus musculus P33175 1027 117000 T379 N G E N V P E T E R L A G E D
Rat Rattus norvegicus Q6QLM7 1027 116897 T379 N G E N V P E T E R L A G E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 R369 E N E L N R W R N G E T V P V
Chicken Gallus gallus Q90640 1225 138905 S390 A P S E N L Q S L M E K N Q S
Frog Xenopus laevis Q91784 1226 138905 L389 P S E N L Q S L M E R N K N L
Zebra Danio Brachydanio rerio XP_691912 851 97123 G262 N K S L S S L G N V I S A L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 E385 A G E T V K A E E Q I N M E D
Honey Bee Apis mellifera XP_395236 988 112484 E389 Q G E T V K P E E Q V N L V E
Nematode Worm Caenorhab. elegans P34540 815 91875 L226 H Q T T K K Q L T G K L Y L V
Sea Urchin Strong. purpuratus P35978 1031 117504 K377 A G E S V P V K E Q G N K N D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 E339 N K A K V N A E L S P A E L K
Conservation
Percent
Protein Identity: 100 97.6 60 99 N.A. 97.6 96.8 N.A. 66.6 26.2 26.1 59 N.A. 56.4 60 41.7 59
Protein Similarity: 100 97.9 70.8 99.7 N.A. 99 98.6 N.A. 80 44.3 45.9 70.6 N.A. 72.1 75.2 56.4 74.7
P-Site Identity: 100 100 20 86.6 N.A. 93.3 93.3 N.A. 6.6 0 13.3 6.6 N.A. 33.3 33.3 0 33.3
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 6.6 20 20 20 N.A. 53.3 46.6 13.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 51.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 7 0 0 0 14 0 0 0 0 40 7 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 34 % D
% Glu: 7 0 67 14 0 0 34 20 54 7 14 0 7 40 20 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 54 0 0 0 0 0 7 0 14 7 0 40 0 0 % G
% His: 7 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % I
% Lys: 0 14 0 7 7 20 0 7 0 0 14 14 14 0 7 % K
% Leu: 7 0 0 14 7 7 7 14 14 0 34 7 7 20 7 % L
% Met: 0 0 0 0 0 0 0 0 7 7 0 0 7 0 0 % M
% Asn: 47 7 0 40 14 7 0 0 14 0 0 27 7 14 0 % N
% Pro: 7 7 0 0 0 40 7 0 0 0 7 0 0 7 0 % P
% Gln: 7 7 0 0 0 14 14 0 0 20 0 0 0 7 0 % Q
% Arg: 0 0 0 0 0 7 0 7 0 34 7 0 0 0 0 % R
% Ser: 0 14 14 7 7 7 7 7 0 7 0 7 0 0 7 % S
% Thr: 0 0 7 20 7 0 0 40 7 0 0 7 0 0 0 % T
% Val: 0 0 0 0 60 0 7 0 0 7 7 0 7 7 14 % V
% Trp: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _