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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5A All Species: 19.7
Human Site: T689 Identified Species: 30.95
UniProt: Q12840 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12840 NP_004975.2 1032 117378 T689 L K D K E P D T Q D A D E V K
Chimpanzee Pan troglodytes XP_509167 1028 117090 T685 L K D K E P D T Q D A D E V K
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 Q555 D Y M Q N M E Q K R R Q L E E
Dog Lupus familis XP_849802 1032 117317 T689 L K D K E P D T Q D A D E V K
Cat Felis silvestris
Mouse Mus musculus P33175 1027 117000 T689 L K D K E P D T Q D A E E V K
Rat Rattus norvegicus Q6QLM7 1027 116897 T689 L K D K E P D T Q D A E E V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 E654 T E Y L Q N V E Q K K R Q L E
Chicken Gallus gallus Q90640 1225 138905 R688 L K E R D R K R Q Y E L L K L
Frog Xenopus laevis Q91784 1226 138905 T760 E V E V L V S T E E A Q R H L
Zebra Danio Brachydanio rerio XP_691912 851 97123 K546 D S E L Q K L K E M A N H Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 L670 H E A R M K S L Q E S M R E A
Honey Bee Apis mellifera XP_395236 988 112484 E681 E A R K R A L E E D V D A L R
Nematode Worm Caenorhab. elegans P34540 815 91875 V510 T A L E E I A V N L D V R Q A
Sea Urchin Strong. purpuratus P35978 1031 117504 E682 Q E D K K R E E E D K M Q S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 A623 T Q G F V R Q A E L S S F S A
Conservation
Percent
Protein Identity: 100 97.6 60 99 N.A. 97.6 96.8 N.A. 66.6 26.2 26.1 59 N.A. 56.4 60 41.7 59
Protein Similarity: 100 97.9 70.8 99.7 N.A. 99 98.6 N.A. 80 44.3 45.9 70.6 N.A. 72.1 75.2 56.4 74.7
P-Site Identity: 100 100 0 100 N.A. 93.3 93.3 N.A. 6.6 20 13.3 13.3 N.A. 6.6 20 6.6 20
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 40 40 33.3 40 N.A. 33.3 40 13.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 51.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 7 0 0 7 7 7 0 0 47 0 7 0 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 40 0 7 0 34 0 0 47 7 27 0 0 0 % D
% Glu: 14 20 20 7 40 0 14 20 34 14 7 14 34 14 14 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 40 0 47 7 14 7 7 7 7 14 0 0 7 40 % K
% Leu: 40 0 7 14 7 0 14 7 0 14 0 7 14 14 14 % L
% Met: 0 0 7 0 7 7 0 0 0 7 0 14 0 0 0 % M
% Asn: 0 0 0 0 7 7 0 0 7 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 7 0 7 14 0 7 7 54 0 0 14 14 14 0 % Q
% Arg: 0 0 7 14 7 20 0 7 0 7 7 7 20 0 7 % R
% Ser: 0 7 0 0 0 0 14 0 0 0 14 7 0 14 0 % S
% Thr: 20 0 0 0 0 0 0 40 0 0 0 0 0 0 0 % T
% Val: 0 7 0 7 7 7 7 7 0 0 7 7 0 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _