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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5A All Species: 22.42
Human Site: T807 Identified Species: 35.24
UniProt: Q12840 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12840 NP_004975.2 1032 117378 T807 L F V Q D V T T R V K K S A E
Chimpanzee Pan troglodytes XP_509167 1028 117090 T803 L F V Q D V T T R V K K S A E
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 K658 K L S S D Y N K L K I E D Q E
Dog Lupus familis XP_849802 1032 117317 T807 L F V Q D V T T R V K K S A E
Cat Felis silvestris
Mouse Mus musculus P33175 1027 117000 T807 L F V Q D V T T R V K K S A E
Rat Rattus norvegicus Q6QLM7 1027 116897 T807 L F V Q D V T T R V K K S A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 E760 K L K A T D Q E K S R K L H E
Chicken Gallus gallus Q90640 1225 138905 S821 S E M D L S L S K Q I E S L E
Frog Xenopus laevis Q91784 1226 138905 S879 L I T E L V S S K V A G S K L
Zebra Danio Brachydanio rerio XP_691912 851 97123 K649 S Q H E A K I K S L T E Y L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 E773 Q Q M T A D Y E K V R Q E D A
Honey Bee Apis mellifera XP_395236 988 112484 V784 Q E E A N K S V K L Q E L I L
Nematode Worm Caenorhab. elegans P34540 815 91875 A613 A A K E S S T A A E H D A E A
Sea Urchin Strong. purpuratus P35978 1031 117504 N804 L F V S D L Q N R V K K A L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 M726 A G G A G V A M A N G K T V Q
Conservation
Percent
Protein Identity: 100 97.6 60 99 N.A. 97.6 96.8 N.A. 66.6 26.2 26.1 59 N.A. 56.4 60 41.7 59
Protein Similarity: 100 97.9 70.8 99.7 N.A. 99 98.6 N.A. 80 44.3 45.9 70.6 N.A. 72.1 75.2 56.4 74.7
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 13.3 13.3 26.6 0 N.A. 6.6 0 6.6 60
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 26.6 40 53.3 26.6 N.A. 33.3 40 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 51.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 20 14 0 7 7 14 0 7 0 14 34 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 47 14 0 0 0 0 0 7 7 7 0 % D
% Glu: 0 14 7 20 0 0 0 14 0 7 0 27 7 7 60 % E
% Phe: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 7 0 7 0 0 0 0 0 7 7 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 7 0 0 7 0 % H
% Ile: 0 7 0 0 0 0 7 0 0 0 14 0 0 7 0 % I
% Lys: 14 0 14 0 0 14 0 14 34 7 40 54 0 7 0 % K
% Leu: 47 14 0 0 14 7 7 0 7 14 0 0 14 20 14 % L
% Met: 0 0 14 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 7 7 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 14 14 0 34 0 0 14 0 0 7 7 7 0 7 14 % Q
% Arg: 0 0 0 0 0 0 0 0 40 0 14 0 0 0 0 % R
% Ser: 14 0 7 14 7 14 14 14 7 7 0 0 47 0 0 % S
% Thr: 0 0 7 7 7 0 40 34 0 0 7 0 7 0 0 % T
% Val: 0 0 40 0 0 47 0 7 0 54 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 7 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _