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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5A All Species: 9.09
Human Site: T933 Identified Species: 14.29
UniProt: Q12840 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12840 NP_004975.2 1032 117378 T933 H Y P A S S P T N P Y G T R S
Chimpanzee Pan troglodytes XP_509167 1028 117090 T929 H Y P A S S P T N P Y G T R S
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 R762 V R D N A D L R C E L P K L E
Dog Lupus familis XP_849802 1032 117317 T933 H Y P A S S P T N P Y G T R S
Cat Felis silvestris
Mouse Mus musculus P33175 1027 117000 P928 P V R P G H Y P A S S P T N P
Rat Rattus norvegicus Q6QLM7 1027 116897 P928 P V R P G H Y P A S S P T N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 L867 L P K L E K R L R A T A E R V
Chicken Gallus gallus Q90640 1225 138905 P1029 S P F D Y I P P K P K T R R Q
Frog Xenopus laevis Q91784 1226 138905 P1032 D S P F D F I P P K P R G K R
Zebra Danio Brachydanio rerio XP_691912 851 97123 E753 E Q E R L R V E H E K L K S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 D877 Q L V R D N A D L R C E L P K
Honey Bee Apis mellifera XP_395236 988 112484 R890 P K L E K R L R A T M E R V K
Nematode Worm Caenorhab. elegans P34540 815 91875 Q717 K L T K V H K Q L V R D N A D
Sea Urchin Strong. purpuratus P35978 1031 117504 G932 H P P P S P G G S T G I R G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 Q830 M A R N E R I Q S L E S L L Q
Conservation
Percent
Protein Identity: 100 97.6 60 99 N.A. 97.6 96.8 N.A. 66.6 26.2 26.1 59 N.A. 56.4 60 41.7 59
Protein Similarity: 100 97.9 70.8 99.7 N.A. 99 98.6 N.A. 80 44.3 45.9 70.6 N.A. 72.1 75.2 56.4 74.7
P-Site Identity: 100 100 0 100 N.A. 6.6 6.6 N.A. 6.6 20 6.6 0 N.A. 0 0 0 20
P-Site Similarity: 100 100 6.6 100 N.A. 6.6 6.6 N.A. 6.6 20 13.3 13.3 N.A. 6.6 0 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 51.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 20 7 0 7 0 20 7 0 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % C
% Asp: 7 0 7 7 14 7 0 7 0 0 0 7 0 0 7 % D
% Glu: 7 0 7 7 14 0 0 7 0 14 7 14 7 0 7 % E
% Phe: 0 0 7 7 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 14 0 7 7 0 0 7 20 7 7 7 % G
% His: 27 0 0 0 0 20 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 14 0 0 0 0 7 0 0 0 % I
% Lys: 7 7 7 7 7 7 7 0 7 7 14 0 14 7 14 % K
% Leu: 7 14 7 7 7 0 14 7 14 7 7 7 14 14 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 14 0 7 0 0 20 0 0 0 7 14 0 % N
% Pro: 20 20 34 20 0 7 27 27 7 27 7 20 0 7 14 % P
% Gln: 7 7 0 0 0 0 0 14 0 0 0 0 0 0 14 % Q
% Arg: 0 7 20 14 0 20 7 14 7 7 7 7 20 34 7 % R
% Ser: 7 7 0 0 27 20 0 0 14 14 14 7 0 7 20 % S
% Thr: 0 0 7 0 0 0 0 20 0 14 7 7 34 0 7 % T
% Val: 7 14 7 0 7 0 7 0 0 7 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 7 0 14 0 0 0 20 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _