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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
31.82
Human Site:
Y139
Identified Species:
50
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
Y139
K
V
S
Y
F
E
I
Y
L
D
K
I
R
D
L
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
Y135
K
V
S
Y
F
E
I
Y
L
D
K
I
R
D
L
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
F32
S
M
D
E
N
L
E
F
H
I
K
V
S
Y
F
Dog
Lupus familis
XP_849802
1032
117317
Y139
K
V
S
Y
F
E
I
Y
L
D
K
I
R
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
Y139
K
V
S
Y
F
E
I
Y
L
D
K
I
R
D
L
Rat
Rattus norvegicus
Q6QLM7
1027
116897
Y139
K
V
S
Y
F
E
I
Y
L
D
K
I
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
E127
Y
S
M
D
E
N
L
E
F
H
I
K
V
S
Y
Chicken
Gallus gallus
Q90640
1225
138905
D147
Y
L
E
I
Y
N
E
D
I
L
D
L
L
C
S
Frog
Xenopus laevis
Q91784
1226
138905
I147
L
E
I
Y
N
E
E
I
L
D
L
L
Y
A
A
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
V23
R
P
L
N
S
S
E
V
T
R
G
D
K
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
Y145
K
V
S
Y
Y
E
I
Y
M
D
K
I
R
D
L
Honey Bee
Apis mellifera
XP_395236
988
112484
Y149
K
V
S
Y
F
E
I
Y
M
D
K
I
R
D
L
Nematode Worm
Caenorhab. elegans
P34540
815
91875
Sea Urchin
Strong. purpuratus
P35978
1031
117504
Y137
K
V
S
Y
F
E
I
Y
M
D
R
I
R
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
G100
G
K
S
Y
T
M
M
G
T
S
I
D
D
P
D
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
0
0
26.6
0
N.A.
86.6
93.3
0
86.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
6.6
26.6
33.3
20
N.A.
100
100
0
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
7
7
0
0
0
7
0
60
7
14
7
54
7
% D
% Glu:
0
7
7
7
7
60
27
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
47
0
0
7
7
0
0
0
0
0
7
% F
% Gly:
7
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
0
0
7
7
0
0
54
7
7
7
14
54
0
0
7
% I
% Lys:
54
7
0
0
0
0
0
0
0
0
54
7
7
0
0
% K
% Leu:
7
7
7
0
0
7
7
0
40
7
7
14
7
0
54
% L
% Met:
0
7
7
0
0
7
7
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
14
14
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
7
7
0
54
0
0
% R
% Ser:
7
7
60
0
7
7
0
0
0
7
0
0
7
7
7
% S
% Thr:
0
0
0
0
7
0
0
0
14
0
0
0
0
0
0
% T
% Val:
0
54
0
0
0
0
0
7
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
0
67
14
0
0
54
0
0
0
0
7
14
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _