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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
23.94
Human Site:
Y417
Identified Species:
37.62
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
Y417
A
P
E
E
R
Q
K
Y
E
E
E
I
R
R
L
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
Y413
A
P
E
E
R
Q
K
Y
E
E
E
I
R
R
L
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
A306
T
P
I
I
D
N
I
A
P
V
V
A
G
I
S
Dog
Lupus familis
XP_849802
1032
117317
Y417
A
P
E
E
R
Q
K
Y
E
E
E
I
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
Y417
A
P
E
E
R
Q
K
Y
E
E
E
I
R
R
L
Rat
Rattus norvegicus
Q6QLM7
1027
116897
Y417
A
P
E
E
R
Q
K
Y
E
E
E
I
R
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
T404
S
V
I
N
D
K
P
T
A
T
I
G
V
T
G
Chicken
Gallus gallus
Q90640
1225
138905
T426
M
L
E
R
I
I
V
T
E
Q
E
N
E
K
M
Frog
Xenopus laevis
Q91784
1226
138905
T424
F
L
E
K
I
I
M
T
E
Q
Q
N
E
K
L
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
T297
L
G
G
N
C
R
T
T
I
V
I
C
C
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
T420
A
A
L
A
A
Q
R
T
A
L
A
N
M
S
A
Honey Bee
Apis mellifera
XP_395236
988
112484
N424
M
P
A
T
P
G
G
N
L
M
A
G
S
L
S
Nematode Worm
Caenorhab. elegans
P34540
815
91875
L261
A
K
N
I
N
K
S
L
T
A
L
G
I
V
I
Sea Urchin
Strong. purpuratus
P35978
1031
117504
K412
K
N
K
W
E
E
E
K
V
K
L
Y
E
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
R374
E
S
E
V
Q
V
W
R
G
G
E
T
V
P
K
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
0
20
20
0
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
13.3
40
46.6
6.6
N.A.
20
6.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
7
7
7
7
0
0
7
14
7
14
7
0
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
7
7
0
0
% C
% Asp:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
54
34
7
7
7
0
47
34
47
0
20
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
7
7
0
7
7
0
20
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
14
14
14
7
0
7
0
14
34
7
7
7
% I
% Lys:
7
7
7
7
0
14
34
7
0
7
0
0
0
14
7
% K
% Leu:
7
14
7
0
0
0
0
7
7
7
14
0
0
7
47
% L
% Met:
14
0
0
0
0
0
7
0
0
7
0
0
7
0
7
% M
% Asn:
0
7
7
14
7
7
0
7
0
0
0
20
0
0
0
% N
% Pro:
0
47
0
0
7
0
7
0
7
0
0
0
0
7
7
% P
% Gln:
0
0
0
0
7
40
0
0
0
14
7
0
0
7
0
% Q
% Arg:
0
0
0
7
34
7
7
7
0
0
0
0
34
34
0
% R
% Ser:
7
7
0
0
0
0
7
0
0
0
0
0
7
14
14
% S
% Thr:
7
0
0
7
0
0
7
34
7
7
0
7
0
7
0
% T
% Val:
0
7
0
7
0
7
7
0
7
14
7
0
14
7
0
% V
% Trp:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _