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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
19.09
Human Site:
Y590
Identified Species:
30
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
Y590
E
F
T
V
A
R
L
Y
I
S
K
I
K
S
E
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
Y586
E
F
T
V
A
R
L
Y
I
S
K
I
K
S
E
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
E463
L
L
L
K
D
L
G
E
I
G
G
I
I
G
T
Dog
Lupus familis
XP_849802
1032
117317
Y590
E
F
T
V
A
R
L
Y
I
S
K
I
K
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
Y590
E
F
T
V
A
R
L
Y
I
S
K
I
K
S
E
Rat
Rattus norvegicus
Q6QLM7
1027
116897
Y590
E
F
T
V
A
R
L
Y
I
S
K
I
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
L562
M
A
S
L
L
K
D
L
A
E
I
G
I
A
V
Chicken
Gallus gallus
Q90640
1225
138905
M590
E
L
I
L
A
L
S
M
A
K
K
D
V
N
Q
Frog
Xenopus laevis
Q91784
1226
138905
E642
T
V
A
K
M
N
Q
E
I
Q
G
M
K
M
Q
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
L454
Q
S
Q
L
V
E
K
L
K
Q
Q
M
L
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
L578
L
T
N
L
L
R
D
L
G
E
V
G
Q
A
I
Honey Bee
Apis mellifera
XP_395236
988
112484
I586
L
G
E
I
G
V
A
I
G
G
D
E
N
L
K
Nematode Worm
Caenorhab. elegans
P34540
815
91875
S418
P
A
P
P
M
L
T
S
T
T
G
P
I
T
D
Sea Urchin
Strong. purpuratus
P35978
1031
117504
F583
E
F
T
M
A
R
L
F
V
S
K
M
K
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
V531
L
T
A
E
L
D
E
V
K
Q
Q
M
L
D
M
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
0
20
13.3
0
N.A.
6.6
0
0
66.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
26.6
40
26.6
33.3
N.A.
26.6
13.3
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
14
0
47
0
7
0
14
0
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
7
14
0
0
0
7
7
0
14
7
% D
% Glu:
47
0
7
7
0
7
7
14
0
14
0
7
0
0
40
% E
% Phe:
0
40
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
0
7
0
14
14
20
14
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
0
0
0
7
47
0
7
40
20
0
7
% I
% Lys:
0
0
0
14
0
7
7
0
14
7
47
0
47
0
7
% K
% Leu:
27
14
7
27
20
20
40
20
0
0
0
0
14
7
0
% L
% Met:
7
0
0
7
14
0
0
7
0
0
0
27
0
7
7
% M
% Asn:
0
0
7
0
0
7
0
0
0
0
0
0
7
7
0
% N
% Pro:
7
0
7
7
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
7
0
7
0
0
0
7
0
0
20
14
0
7
0
20
% Q
% Arg:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
7
0
0
0
7
7
0
40
0
0
0
34
0
% S
% Thr:
7
14
40
0
0
0
7
0
7
7
0
0
0
14
7
% T
% Val:
0
7
0
34
7
7
0
7
7
0
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _