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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
21.21
Human Site:
Y661
Identified Species:
33.33
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
Y661
K
R
H
L
E
E
S
Y
D
S
L
S
D
E
L
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
Y657
K
R
H
L
E
E
S
Y
D
S
L
S
D
E
L
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
R527
R
K
M
N
A
S
E
R
E
L
A
A
C
Q
L
Dog
Lupus familis
XP_849802
1032
117317
Y661
K
R
H
L
E
E
S
Y
D
S
L
S
D
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
Y661
K
R
H
L
E
E
S
Y
D
S
L
S
D
E
L
Rat
Rattus norvegicus
Q6QLM7
1027
116897
Y661
K
R
H
L
E
E
S
Y
D
S
L
S
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
E626
N
K
K
M
E
E
N
E
K
E
L
A
A
C
Q
Chicken
Gallus gallus
Q90640
1225
138905
M660
R
V
Q
L
M
R
Q
M
K
E
D
A
E
K
F
Frog
Xenopus laevis
Q91784
1226
138905
K732
K
E
A
M
E
K
R
K
D
S
Q
S
K
G
M
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
T518
S
Q
E
V
E
D
K
T
K
E
F
E
A
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
S642
M
E
T
Q
Q
A
D
S
N
K
K
I
S
E
Y
Honey Bee
Apis mellifera
XP_395236
988
112484
R653
E
K
D
L
A
E
C
R
L
L
I
S
Q
H
E
Nematode Worm
Caenorhab. elegans
P34540
815
91875
E482
E
N
E
E
L
I
R
E
E
N
N
R
F
Q
K
Sea Urchin
Strong. purpuratus
P35978
1031
117504
L654
K
R
H
L
E
D
S
L
D
M
L
N
E
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
S595
L
D
A
L
F
E
I
S
S
A
G
D
A
I
P
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
20
6.6
33.3
6.6
N.A.
6.6
20
0
60
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
46.6
33.3
53.3
26.6
N.A.
20
40
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
14
7
0
0
0
7
7
20
20
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
0
% C
% Asp:
0
7
7
0
0
14
7
0
47
0
7
7
34
0
0
% D
% Glu:
14
14
14
7
60
54
7
14
14
20
0
7
14
47
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
7
0
7
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% G
% His:
0
0
40
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
7
7
0
0
0
7
7
0
7
7
% I
% Lys:
47
20
7
0
0
7
7
7
20
7
7
0
7
7
7
% K
% Leu:
7
0
0
60
7
0
0
7
7
14
47
0
0
7
40
% L
% Met:
7
0
7
14
7
0
0
7
0
7
0
0
0
0
7
% M
% Asn:
7
7
0
7
0
0
7
0
7
7
7
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
7
7
7
7
0
7
0
0
0
7
0
7
14
7
% Q
% Arg:
14
40
0
0
0
7
14
14
0
0
0
7
0
0
0
% R
% Ser:
7
0
0
0
0
7
40
14
7
40
0
47
7
0
7
% S
% Thr:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _