KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5A
All Species:
10.91
Human Site:
Y946
Identified Species:
17.14
UniProt:
Q12840
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12840
NP_004975.2
1032
117378
Y946
R
S
P
E
C
I
S
Y
T
N
S
L
F
Q
N
Chimpanzee
Pan troglodytes
XP_509167
1028
117090
Y942
R
S
P
E
C
I
S
Y
T
N
S
L
F
Q
N
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
T775
L
E
K
R
L
R
A
T
A
E
R
V
K
A
L
Dog
Lupus familis
XP_849802
1032
117317
Y946
R
S
P
E
C
I
S
Y
T
N
S
L
F
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
P33175
1027
117000
P941
N
P
Y
G
T
R
S
P
E
C
I
S
Y
T
N
Rat
Rattus norvegicus
Q6QLM7
1027
116897
P941
N
P
Y
G
T
R
S
P
E
C
I
S
Y
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
A880
R
V
K
A
L
E
S
A
L
K
E
A
K
E
N
Chicken
Gallus gallus
Q90640
1225
138905
R1042
R
Q
T
V
A
K
P
R
A
P
T
P
E
M
N
Frog
Xenopus laevis
Q91784
1226
138905
S1045
K
R
R
T
N
A
K
S
A
A
V
I
L
E
D
Zebra Danio
Brachydanio rerio
XP_691912
851
97123
R766
S
T
D
Q
E
K
S
R
K
L
H
E
L
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
R890
P
K
L
E
K
R
L
R
C
T
M
E
R
V
K
Honey Bee
Apis mellifera
XP_395236
988
112484
L903
V
K
A
L
E
T
A
L
R
D
A
K
E
G
A
Nematode Worm
Caenorhab. elegans
P34540
815
91875
P730
A
D
L
R
V
E
L
P
K
M
E
A
R
L
R
Sea Urchin
Strong. purpuratus
P35978
1031
117504
R945
G
G
G
Y
S
G
I
R
G
G
G
S
P
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
M843
L
Q
E
S
Q
E
K
M
A
Q
A
N
H
K
F
Conservation
Percent
Protein Identity:
100
97.6
60
99
N.A.
97.6
96.8
N.A.
66.6
26.2
26.1
59
N.A.
56.4
60
41.7
59
Protein Similarity:
100
97.9
70.8
99.7
N.A.
99
98.6
N.A.
80
44.3
45.9
70.6
N.A.
72.1
75.2
56.4
74.7
P-Site Identity:
100
100
0
100
N.A.
13.3
13.3
N.A.
20
13.3
0
6.6
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
13.3
100
N.A.
20
20
N.A.
26.6
20
26.6
20
N.A.
6.6
20
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
7
7
14
7
27
7
14
14
0
7
7
% A
% Cys:
0
0
0
0
20
0
0
0
7
14
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
0
0
0
0
7
0
0
0
0
7
% D
% Glu:
0
7
7
27
14
20
0
0
14
7
14
14
14
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
7
% F
% Gly:
7
7
7
14
0
7
0
0
7
7
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% H
% Ile:
0
0
0
0
0
20
7
0
0
0
14
7
0
0
7
% I
% Lys:
7
14
14
0
7
14
14
0
14
7
0
7
14
7
7
% K
% Leu:
14
0
14
7
14
0
14
7
7
7
0
20
14
7
7
% L
% Met:
0
0
0
0
0
0
0
7
0
7
7
0
0
7
7
% M
% Asn:
14
0
0
0
7
0
0
0
0
20
0
7
0
0
47
% N
% Pro:
7
14
20
0
0
0
7
20
0
7
0
7
7
0
0
% P
% Gln:
0
14
0
7
7
0
0
0
0
7
0
0
0
20
0
% Q
% Arg:
34
7
7
14
0
27
0
27
7
0
7
0
14
0
7
% R
% Ser:
7
20
0
7
7
0
47
7
0
0
20
20
0
0
0
% S
% Thr:
0
7
7
7
14
7
0
7
20
7
7
0
0
20
0
% T
% Val:
7
7
0
7
7
0
0
0
0
0
7
7
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
7
0
0
0
20
0
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _