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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX4
All Species:
13.64
Human Site:
S131
Identified Species:
25
UniProt:
Q12846
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12846
NP_004595.2
297
34180
S131
K
T
Q
H
G
V
L
S
Q
Q
F
V
E
L
I
Chimpanzee
Pan troglodytes
XP_001138080
288
33353
L122
R
R
T
Q
H
S
V
L
S
R
K
F
V
E
A
Rhesus Macaque
Macaca mulatta
XP_001095454
133
15513
Dog
Lupus familis
XP_547039
297
34263
S131
K
T
Q
H
G
V
L
S
Q
Q
F
V
E
L
I
Cat
Felis silvestris
Mouse
Mus musculus
P70452
298
34146
S131
K
T
Q
H
G
V
L
S
Q
Q
F
V
E
L
I
Rat
Rattus norvegicus
Q08850
298
34191
S131
K
T
Q
H
G
V
L
S
Q
Q
F
V
E
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517537
254
29106
C97
F
V
E
L
I
N
K
C
N
V
T
Q
S
E
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089849
295
34504
L129
R
K
T
Q
H
G
V
L
S
Q
Q
F
I
E
L
Zebra Danio
Brachydanio rerio
NP_956515
297
33901
L132
R
R
T
Q
H
G
V
L
S
R
E
F
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
L126
R
K
T
Q
H
S
T
L
S
R
K
F
V
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
L124
R
K
T
Q
H
S
T
L
S
R
R
F
V
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZQZ8
305
34465
G135
T
S
V
V
S
G
L
G
K
K
L
K
D
M
M
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
R123
Q
A
Q
A
E
N
C
R
Q
K
F
L
K
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
44.1
93.9
N.A.
90.2
89.5
N.A.
71
N.A.
52.8
52.5
N.A.
41.4
N.A.
38
N.A.
Protein Similarity:
100
67
44.4
96.9
N.A.
96.3
95.9
N.A.
80.4
N.A.
75.4
75.4
N.A.
63.2
N.A.
60.2
N.A.
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
0
N.A.
6.6
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
20
0
100
N.A.
100
100
N.A.
6.6
N.A.
26.6
26.6
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
51.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
8
0
31
47
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
39
39
0
0
0
% F
% Gly:
0
0
0
0
31
24
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
31
39
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
39
% I
% Lys:
31
24
0
0
0
0
8
0
8
16
16
8
8
0
0
% K
% Leu:
0
0
0
8
0
0
39
39
0
0
8
8
8
39
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
16
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
39
39
0
0
0
0
39
39
8
8
0
0
0
% Q
% Arg:
39
16
0
0
0
0
0
8
0
31
8
0
0
0
0
% R
% Ser:
0
8
0
0
8
24
0
31
39
0
0
0
8
0
0
% S
% Thr:
8
31
39
0
0
0
16
0
0
0
8
0
0
0
0
% T
% Val:
0
8
8
8
0
31
24
0
0
8
0
31
24
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _