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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX4
All Species:
13.64
Human Site:
S247
Identified Species:
25
UniProt:
Q12846
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12846
NP_004595.2
297
34180
S247
R
I
E
K
N
I
L
S
S
A
D
Y
V
E
R
Chimpanzee
Pan troglodytes
XP_001138080
288
33353
N238
N
I
E
R
N
V
M
N
A
T
D
Y
V
E
H
Rhesus Macaque
Macaca mulatta
XP_001095454
133
15513
E89
E
L
Q
N
L
R
D
E
I
K
Q
L
G
R
E
Dog
Lupus familis
XP_547039
297
34263
S247
R
I
E
K
N
I
L
S
S
A
D
Y
V
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P70452
298
34146
S247
R
I
E
K
N
I
L
S
S
A
D
Y
V
E
R
Rat
Rattus norvegicus
Q08850
298
34191
S247
R
I
E
K
N
I
L
S
S
A
D
Y
V
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517537
254
29106
R210
T
S
A
D
Y
V
V
R
G
Q
E
H
V
A
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089849
295
34504
R245
N
I
E
K
N
I
M
R
S
N
D
Y
V
E
K
Zebra Danio
Brachydanio rerio
NP_956515
297
33901
M248
R
I
E
S
N
I
K
M
S
H
D
Y
V
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
H242
R
I
E
Y
H
V
E
H
A
M
D
Y
V
Q
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
H240
R
I
E
Y
N
V
E
H
A
K
E
F
V
D
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZQZ8
305
34465
K253
D
I
E
S
N
V
S
K
A
S
S
F
V
M
R
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
D241
V
I
D
K
N
V
E
D
A
Q
Q
D
V
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
44.1
93.9
N.A.
90.2
89.5
N.A.
71
N.A.
52.8
52.5
N.A.
41.4
N.A.
38
N.A.
Protein Similarity:
100
67
44.4
96.9
N.A.
96.3
95.9
N.A.
80.4
N.A.
75.4
75.4
N.A.
63.2
N.A.
60.2
N.A.
P-Site Identity:
100
46.6
0
100
N.A.
100
100
N.A.
6.6
N.A.
66.6
66.6
N.A.
40
N.A.
40
N.A.
P-Site Similarity:
100
80
13.3
100
N.A.
100
100
N.A.
33.3
N.A.
80
73.3
N.A.
66.6
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
51.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
39
31
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
8
8
0
0
62
8
0
8
0
% D
% Glu:
8
0
77
0
0
0
24
8
0
0
16
0
0
62
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
16
0
8
0
8
0
0
8
% H
% Ile:
0
85
0
0
0
47
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
47
0
0
8
8
0
16
0
0
0
0
16
% K
% Leu:
0
8
0
0
8
0
31
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
16
8
0
8
0
0
0
8
0
% M
% Asn:
16
0
0
8
77
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
16
16
0
0
8
8
% Q
% Arg:
54
0
0
8
0
8
0
16
0
0
0
0
0
8
47
% R
% Ser:
0
8
0
16
0
0
8
31
47
8
8
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
8
0
0
0
0
47
8
0
0
0
0
0
93
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
8
0
0
0
0
0
0
62
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _