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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX4
All Species:
11.21
Human Site:
S36
Identified Species:
20.56
UniProt:
Q12846
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12846
NP_004595.2
297
34180
S36
P
G
T
A
R
L
G
S
P
D
E
E
F
F
H
Chimpanzee
Pan troglodytes
XP_001138080
288
33353
N41
H
Q
V
E
E
I
R
N
S
I
D
K
I
T
Q
Rhesus Macaque
Macaca mulatta
XP_001095454
133
15513
Dog
Lupus familis
XP_547039
297
34263
S36
P
G
T
A
R
L
G
S
P
D
E
E
F
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70452
298
34146
S36
S
G
A
A
R
L
G
S
P
D
D
E
F
F
Q
Rat
Rattus norvegicus
Q08850
298
34191
S36
S
G
A
A
R
L
S
S
P
D
D
E
F
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517537
254
29106
L26
E
K
Q
Q
I
T
I
L
A
T
P
L
P
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089849
295
34504
E36
N
G
S
K
D
E
T
E
I
N
E
Q
F
L
Q
Zebra Danio
Brachydanio rerio
NP_956515
297
33901
N35
P
G
S
G
T
S
A
N
E
D
K
E
N
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
A38
S
Y
M
D
D
F
F
A
Q
V
E
E
I
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
A50
R
G
S
V
D
I
I
A
N
N
V
E
E
V
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZQZ8
305
34465
A52
S
V
K
E
D
M
K
A
V
D
E
I
H
K
R
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
D35
T
G
H
S
D
G
S
D
D
F
V
A
F
M
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
44.1
93.9
N.A.
90.2
89.5
N.A.
71
N.A.
52.8
52.5
N.A.
41.4
N.A.
38
N.A.
Protein Similarity:
100
67
44.4
96.9
N.A.
96.3
95.9
N.A.
80.4
N.A.
75.4
75.4
N.A.
63.2
N.A.
60.2
N.A.
P-Site Identity:
100
0
0
93.3
N.A.
73.3
66.6
N.A.
0
N.A.
20
26.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
0
93.3
N.A.
80
73.3
N.A.
0
N.A.
40
46.6
N.A.
20
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
51.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
31
0
0
8
24
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
39
0
0
8
8
47
24
0
0
0
8
% D
% Glu:
8
0
0
16
8
8
0
8
8
0
39
54
8
16
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
8
0
0
47
31
0
% F
% Gly:
0
62
0
8
0
8
24
0
0
0
0
0
0
0
8
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
8
16
16
0
8
8
0
8
16
0
0
% I
% Lys:
0
8
8
8
0
0
8
0
0
0
8
8
0
8
8
% K
% Leu:
0
0
0
0
0
31
0
8
0
0
0
8
0
8
0
% L
% Met:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
0
16
8
16
0
0
8
0
8
% N
% Pro:
24
0
0
0
0
0
0
0
31
0
8
0
8
0
0
% P
% Gln:
0
8
8
8
0
0
0
0
8
0
0
8
0
0
39
% Q
% Arg:
8
0
0
0
31
0
8
0
0
0
0
0
0
8
8
% R
% Ser:
31
0
24
8
0
8
16
31
8
0
0
0
0
0
0
% S
% Thr:
8
0
16
0
8
8
8
0
0
8
0
0
0
8
0
% T
% Val:
0
8
8
8
0
0
0
0
8
8
16
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _