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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX4
All Species:
26.36
Human Site:
T193
Identified Species:
48.33
UniProt:
Q12846
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12846
NP_004595.2
297
34180
T193
V
S
N
I
L
K
D
T
Q
V
T
R
Q
A
L
Chimpanzee
Pan troglodytes
XP_001138080
288
33353
S184
T
S
D
I
I
S
D
S
Q
I
T
R
Q
A
L
Rhesus Macaque
Macaca mulatta
XP_001095454
133
15513
D38
T
A
R
L
G
S
P
D
E
E
F
F
Q
K
V
Dog
Lupus familis
XP_547039
297
34263
T193
V
S
N
I
L
K
D
T
Q
V
T
R
Q
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P70452
298
34146
T193
V
S
N
I
L
K
D
T
Q
V
T
R
Q
A
L
Rat
Rattus norvegicus
Q08850
298
34191
T193
V
S
N
I
L
K
D
T
Q
V
T
R
Q
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517537
254
29106
I159
T
R
Q
A
L
N
E
I
S
A
R
H
G
E
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089849
295
34504
T191
T
C
N
I
L
K
D
T
Q
L
T
K
Q
A
L
Zebra Danio
Brachydanio rerio
NP_956515
297
33901
A194
T
Q
N
I
L
N
D
A
K
A
T
R
Q
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
T188
T
Q
G
I
I
M
E
T
Q
Q
A
K
Q
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
T186
T
Q
G
I
I
T
D
T
Q
Q
A
K
Q
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZQZ8
305
34465
Q197
L
Q
K
A
I
Q
E
Q
G
R
G
Q
V
M
D
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
N185
S
Q
A
L
L
N
A
N
R
R
G
E
A
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
44.1
93.9
N.A.
90.2
89.5
N.A.
71
N.A.
52.8
52.5
N.A.
41.4
N.A.
38
N.A.
Protein Similarity:
100
67
44.4
96.9
N.A.
96.3
95.9
N.A.
80.4
N.A.
75.4
75.4
N.A.
63.2
N.A.
60.2
N.A.
P-Site Identity:
100
60
6.6
100
N.A.
100
100
N.A.
6.6
N.A.
73.3
60
N.A.
33.3
N.A.
40
N.A.
P-Site Similarity:
100
86.6
33.3
100
N.A.
100
100
N.A.
20
N.A.
86.6
66.6
N.A.
53.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
51.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
16
0
0
8
8
0
16
16
0
8
54
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
62
8
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
24
0
8
8
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
16
0
8
0
0
0
8
0
16
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
70
31
0
0
8
0
8
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
39
0
0
8
0
0
24
0
16
0
% K
% Leu:
8
0
0
16
62
0
0
0
0
8
0
0
0
0
70
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
47
0
0
24
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
39
8
0
0
8
0
8
62
16
0
8
77
0
0
% Q
% Arg:
0
8
8
0
0
0
0
0
8
16
8
47
0
0
0
% R
% Ser:
8
39
0
0
0
16
0
8
8
0
0
0
0
0
0
% S
% Thr:
54
0
0
0
0
8
0
54
0
0
54
0
0
16
8
% T
% Val:
31
0
0
0
0
0
0
0
0
31
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _