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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFIA All Species: 22.73
Human Site: S337 Identified Species: 62.5
UniProt: Q12857 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12857 NP_001128145.1 509 55944 S337 G F S S P S P S Q T S S L G T
Chimpanzee Pan troglodytes XP_001157608 527 57995 S337 G F S S P S P S Q T S S L G T
Rhesus Macaque Macaca mulatta XP_001084241 532 58521 S360 G F S S P S P S Q T S S L G T
Dog Lupus familis XP_536691 507 55644 S335 G F S S P S P S Q T S S L G T
Cat Felis silvestris
Mouse Mus musculus Q02780 532 58535 S360 G F S S P S P S Q T S S L G T
Rat Rattus norvegicus P09414 509 55958 S337 G F S S P S P S Q T S S L G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P17923 522 57455 K337 M P S P T A L K K S E K S G F
Frog Xenopus laevis NP_001154859 499 55166 P331 S P F H S P S P Q D T S P R I
Zebra Danio Brachydanio rerio NP_001073431 481 53108 K318 E V E P A G Y K L R G S L A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 94.9 98.4 N.A. 94.1 99.8 N.A. N.A. 96.3 63.4 85.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.5 95.1 99 N.A. 95.1 100 N.A. N.A. 96.9 74.6 90.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 33.3 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 12 0 0 0 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % D
% Glu: 12 0 12 0 0 0 0 0 0 0 12 0 0 0 0 % E
% Phe: 0 67 12 0 0 0 0 0 0 0 0 0 0 0 12 % F
% Gly: 67 0 0 0 0 12 0 0 0 0 12 0 0 78 0 % G
% His: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 0 0 0 0 23 12 0 0 12 0 0 0 % K
% Leu: 0 0 0 0 0 0 12 0 12 0 0 0 78 0 0 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 23 0 23 67 12 67 12 0 0 0 0 12 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 12 0 0 0 12 0 % R
% Ser: 12 0 78 67 12 67 12 67 0 12 67 89 12 0 12 % S
% Thr: 0 0 0 0 12 0 0 0 0 67 12 0 0 0 67 % T
% Val: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _