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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MERTK All Species: 23.33
Human Site: Y812 Identified Species: 57.04
UniProt: Q12866 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12866 NP_006334.2 999 110249 Y812 Q N H E M Y D Y L L H G H R L
Chimpanzee Pan troglodytes XP_515690 1233 133559 Y1046 Q N H E M Y D Y L L H G H R L
Rhesus Macaque Macaca mulatta XP_001086951 1001 110501 Y814 Q N H E M Y D Y L L H G H R L
Dog Lupus familis XP_540175 1028 113128 Y841 Q N H E M Y D Y L L H G H R L
Cat Felis silvestris
Mouse Mus musculus Q60805 994 110139 Y807 Q N H E M Y D Y L L H G H R L
Rat Rattus norvegicus P57097 994 109405 Y807 Q N H E M Y D Y L L H G H R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519173 260 28358 C77 V I I L A C L C G V T V I G L
Chicken Gallus gallus Q98949 873 96384 S690 V K W L A L E S L A D N L Y T
Frog Xenopus laevis Q8QFP9 880 97916 H697 A D N V Y T V H S D V W A F G
Zebra Danio Brachydanio rerio Q9YI66 874 97580 Q691 A D N V Y T T Q S D V W A F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.2 95.5 82 N.A. 81.1 80.5 N.A. 21.8 37.9 37.3 37.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 80.6 97.1 87.3 N.A. 87.7 88.4 N.A. 23.7 55 54.1 54.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 6.6 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 13.3 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 20 0 0 0 0 10 0 0 20 0 0 % A
% Cys: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 0 0 60 0 0 20 10 0 0 0 0 % D
% Glu: 0 0 0 60 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 60 0 10 20 % G
% His: 0 0 60 0 0 0 0 10 0 0 60 0 60 0 0 % H
% Ile: 0 10 10 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 20 0 10 10 0 70 60 0 0 10 0 70 % L
% Met: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 60 20 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 60 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 0 % R
% Ser: 0 0 0 0 0 0 0 10 20 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 20 10 0 0 0 10 0 0 0 10 % T
% Val: 20 0 0 20 0 0 10 0 0 10 20 10 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 20 0 0 0 % W
% Tyr: 0 0 0 0 20 60 0 60 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _