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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS8
All Species:
23.94
Human Site:
S435
Identified Species:
43.89
UniProt:
Q12872
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12872
NP_004583.2
951
104822
S435
E
T
S
S
G
A
T
S
T
T
T
T
T
S
A
Chimpanzee
Pan troglodytes
XP_509484
951
104645
S435
E
T
S
S
G
A
T
S
T
T
T
T
T
S
A
Rhesus Macaque
Macaca mulatta
XP_001105117
948
104521
S435
E
T
S
S
G
A
T
S
T
T
T
T
T
S
A
Dog
Lupus familis
XP_534636
940
103748
S432
E
T
S
S
G
V
T
S
T
I
T
T
S
A
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_758480
945
104172
S435
E
P
S
S
G
V
T
S
T
T
T
T
T
S
A
Rat
Rattus norvegicus
NP_001030096
791
87373
Q330
I
P
P
P
P
D
I
Q
P
V
I
D
K
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521616
918
101971
S408
S
S
S
G
V
T
T
S
T
S
S
T
S
P
L
Chicken
Gallus gallus
XP_415093
949
105104
T433
S
S
S
G
L
T
S
T
T
T
S
T
S
T
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957462
366
41835
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12297
963
106122
A443
N
T
S
A
L
A
L
A
Q
N
Y
S
S
E
S
Honey Bee
Apis mellifera
XP_392191
993
109374
T479
M
V
N
S
S
Q
I
T
T
N
E
T
Q
L
P
Nematode Worm
Caenorhab. elegans
Q10580
749
86291
A289
V
T
P
E
K
P
G
A
I
G
P
R
K
K
P
Sea Urchin
Strong. purpuratus
XP_001193164
899
100856
L422
Q
L
P
P
P
G
F
L
P
G
V
G
E
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.4
89.6
N.A.
88.9
74.5
N.A.
80.4
80
N.A.
27.7
N.A.
26.3
22.3
24
30.4
Protein Similarity:
100
99.2
98.5
93.2
N.A.
93.2
78.6
N.A.
86
87.5
N.A.
32.5
N.A.
43
39
40
46
P-Site Identity:
100
100
100
66.6
N.A.
86.6
6.6
N.A.
33.3
26.6
N.A.
0
N.A.
20
20
6.6
0
P-Site Similarity:
100
100
100
80
N.A.
86.6
6.6
N.A.
60
66.6
N.A.
0
N.A.
53.3
33.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
31
0
16
0
0
0
0
0
8
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
39
0
0
8
0
0
0
0
0
0
8
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
16
39
8
8
0
0
16
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
16
0
8
8
8
0
0
0
8
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
16
8
0
% K
% Leu:
0
8
0
0
16
0
8
8
0
0
0
0
0
16
16
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
16
0
0
0
0
0
% N
% Pro:
0
16
24
16
16
8
0
0
16
0
8
0
0
16
16
% P
% Gln:
8
0
0
0
0
8
0
8
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
16
16
62
47
8
0
8
47
0
8
16
8
31
31
8
% S
% Thr:
0
47
0
0
0
16
47
16
62
39
39
62
31
8
0
% T
% Val:
8
8
0
0
8
16
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _