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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS8 All Species: 13.33
Human Site: S745 Identified Species: 24.44
UniProt: Q12872 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12872 NP_004583.2 951 104822 S745 P D R P S S K S K D P P R E E
Chimpanzee Pan troglodytes XP_509484 951 104645 S745 P D R P S S K S K D P P R E E
Rhesus Macaque Macaca mulatta XP_001105117 948 104521 S745 P D R P S S K S K D P P R E E
Dog Lupus familis XP_534636 940 103748 K739 A P E G P S S K S K D P P R E
Cat Felis silvestris
Mouse Mus musculus NP_758480 945 104172 C742 P E R P S N R C R D P P R E E
Rat Rattus norvegicus NP_001030096 791 87373 D590 R P S S R C R D P P R E E E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521616 918 101971 C717 S E R P S S K C K D P P R T E
Chicken Gallus gallus XP_415093 949 105104 S746 A E R P S S K S R D P P R D E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957462 366 41835 E166 A G K E A D Q E Q L E E E G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12297 963 106122 I741 D S V R S I P I T Y F G P D D
Honey Bee Apis mellifera XP_392191 993 109374 E776 R N A L L L E E S D E D M E E
Nematode Worm Caenorhab. elegans Q10580 749 86291 R549 P R D E S S F R F D P D L D E
Sea Urchin Strong. purpuratus XP_001193164 899 100856 D698 G N H Q R L E D R L A M A A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.4 89.6 N.A. 88.9 74.5 N.A. 80.4 80 N.A. 27.7 N.A. 26.3 22.3 24 30.4
Protein Similarity: 100 99.2 98.5 93.2 N.A. 93.2 78.6 N.A. 86 87.5 N.A. 32.5 N.A. 43 39 40 46
P-Site Identity: 100 100 100 20 N.A. 66.6 6.6 N.A. 73.3 73.3 N.A. 6.6 N.A. 6.6 20 40 0
P-Site Similarity: 100 100 100 20 N.A. 93.3 13.3 N.A. 80 93.3 N.A. 33.3 N.A. 20 33.3 46.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 8 0 8 0 0 0 0 0 8 0 8 8 0 % A
% Cys: 0 0 0 0 0 8 0 16 0 0 0 0 0 0 0 % C
% Asp: 8 24 8 0 0 8 0 16 0 62 8 16 0 24 8 % D
% Glu: 0 24 8 16 0 0 16 16 0 0 16 16 16 47 77 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 8 0 0 0 0 % F
% Gly: 8 8 0 8 0 0 0 0 0 0 0 8 0 8 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 39 8 31 8 0 0 0 0 0 % K
% Leu: 0 0 0 8 8 16 0 0 0 16 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % M
% Asn: 0 16 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 39 16 0 47 8 0 8 0 8 8 54 54 16 0 0 % P
% Gln: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 0 % Q
% Arg: 16 8 47 8 16 0 16 8 24 0 8 0 47 8 16 % R
% Ser: 8 8 8 8 62 54 8 31 16 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % T
% Val: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _