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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS8 All Species: 7.88
Human Site: S806 Identified Species: 14.44
UniProt: Q12872 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12872 NP_004583.2 951 104822 S806 V R R S R S R S R S P R R R A
Chimpanzee Pan troglodytes XP_509484 951 104645 S806 V R R S R S R S R S P R R R A
Rhesus Macaque Macaca mulatta XP_001105117 948 104521 R803 Y R T V R R S R S R S R S P R
Dog Lupus familis XP_534636 940 103748 R795 P S A Y R T A R R S R S R S R
Cat Felis silvestris
Mouse Mus musculus NP_758480 945 104172 R800 Y R T V R R S R S R S R S P R
Rat Rattus norvegicus NP_001030096 791 87373 R646 Y R T V R R S R S R S R S P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521616 918 101971 R773 P S A Y R T V R R S R S R S R
Chicken Gallus gallus XP_415093 949 105104 S804 A Y R T V R H S R S R S R S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957462 366 41835 Q222 E I V L K A K Q A G N S Q F D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12297 963 106122 T803 S K P V L P P T A A P P P A A
Honey Bee Apis mellifera XP_392191 993 109374 V833 T S V E K E N V V M D S G G C
Nematode Worm Caenorhab. elegans Q10580 749 86291 Q605 I F M E K L L Q E K K A K K L
Sea Urchin Strong. purpuratus XP_001193164 899 100856 R755 S D P E R S Y R E D S E R S H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.4 89.6 N.A. 88.9 74.5 N.A. 80.4 80 N.A. 27.7 N.A. 26.3 22.3 24 30.4
Protein Similarity: 100 99.2 98.5 93.2 N.A. 93.2 78.6 N.A. 86 87.5 N.A. 32.5 N.A. 43 39 40 46
P-Site Identity: 100 100 20 26.6 N.A. 20 20 N.A. 26.6 33.3 N.A. 0 N.A. 13.3 0 0 20
P-Site Similarity: 100 100 20 33.3 N.A. 20 20 N.A. 33.3 40 N.A. 26.6 N.A. 33.3 6.6 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 0 0 8 8 0 16 8 0 8 0 8 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 8 0 0 0 0 0 0 0 8 8 0 0 0 8 % D
% Glu: 8 0 0 24 0 8 0 0 16 0 0 8 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 24 0 8 0 0 8 8 0 8 8 0 % K
% Leu: 0 0 0 8 8 8 8 0 0 0 0 0 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % N
% Pro: 16 0 16 0 0 8 8 0 0 0 24 8 8 24 8 % P
% Gln: 0 0 0 0 0 0 0 16 0 0 0 0 8 0 0 % Q
% Arg: 0 39 24 0 62 31 16 47 39 24 24 39 47 16 39 % R
% Ser: 16 24 0 16 0 24 24 24 24 39 31 39 24 31 0 % S
% Thr: 8 0 24 8 0 16 0 8 0 0 0 0 0 0 0 % T
% Val: 16 0 16 31 8 0 8 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 24 8 0 16 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _