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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS8 All Species: 18.79
Human Site: S872 Identified Species: 34.44
UniProt: Q12872 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12872 NP_004583.2 951 104822 S872 R S Q S V S P S K Q A A P R P
Chimpanzee Pan troglodytes XP_509484 951 104645 S872 R S Q S V S P S K Q A A P R P
Rhesus Macaque Macaca mulatta XP_001105117 948 104521 V869 S K A R S Q S V S P S K Q A A
Dog Lupus familis XP_534636 940 103748 S861 R T E S K A G S Q S A S P S K
Cat Felis silvestris
Mouse Mus musculus NP_758480 945 104172 T866 A K A R S Q S T S P S K Q A A
Rat Rattus norvegicus NP_001030096 791 87373 T712 A K A R S Q S T S P S K Q A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521616 918 101971 S839 R T K S K A R S P S G S P S K
Chicken Gallus gallus XP_415093 949 105104 S870 K S R A R S P S P A V S P G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957462 366 41835 F288 N Y L H P S L F A P K K C S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12297 963 106122 S869 R R R R Q K S S R L S R E P S
Honey Bee Apis mellifera XP_392191 993 109374 G899 S G L P K G A G G A A A N Q T
Nematode Worm Caenorhab. elegans Q10580 749 86291 S671 N R I N S L L S E S G F E P V
Sea Urchin Strong. purpuratus XP_001193164 899 100856 S821 R R K R H S K S R S P S P R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.4 89.6 N.A. 88.9 74.5 N.A. 80.4 80 N.A. 27.7 N.A. 26.3 22.3 24 30.4
Protein Similarity: 100 99.2 98.5 93.2 N.A. 93.2 78.6 N.A. 86 87.5 N.A. 32.5 N.A. 43 39 40 46
P-Site Identity: 100 100 0 33.3 N.A. 0 0 N.A. 26.6 33.3 N.A. 6.6 N.A. 13.3 13.3 6.6 33.3
P-Site Similarity: 100 100 6.6 66.6 N.A. 13.3 13.3 N.A. 53.3 60 N.A. 6.6 N.A. 33.3 20 20 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 24 8 0 16 8 0 8 16 31 24 0 24 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 8 0 0 0 16 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 0 8 8 8 8 0 16 0 0 8 0 % G
% His: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 24 16 0 24 8 8 0 16 0 8 31 0 0 31 % K
% Leu: 0 0 16 0 0 8 16 0 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 8 8 0 24 0 16 31 8 0 47 16 16 % P
% Gln: 0 0 16 0 8 24 0 0 8 16 0 0 24 8 0 % Q
% Arg: 47 24 16 39 8 0 8 0 16 0 0 8 0 24 8 % R
% Ser: 16 24 0 31 31 39 31 62 24 31 31 31 0 24 8 % S
% Thr: 0 16 0 0 0 0 0 16 0 0 0 0 0 0 8 % T
% Val: 0 0 0 0 16 0 0 8 0 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _