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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS8 All Species: 7.88
Human Site: T767 Identified Species: 14.44
UniProt: Q12872 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.42
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12872 NP_004583.2 951 104822 T767 K H K K R S R T R S R S P K Y
Chimpanzee Pan troglodytes XP_509484 951 104645 T767 K H K K R S R T R S R S P K Y
Rhesus Macaque Macaca mulatta XP_001105117 948 104521 R764 K K K K H K K R S R T R S R S
Dog Lupus familis XP_534636 940 103748 H756 K E R K K K K H K K R S R T R
Cat Felis silvestris
Mouse Mus musculus NP_758480 945 104172 R761 K K K K H K K R S R T R S R S
Rat Rattus norvegicus NP_001030096 791 87373 R607 K K K K H K K R S R T R S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521616 918 101971 K734 E K K K K K H K K R S R T R S
Chicken Gallus gallus XP_415093 949 105104 R765 K R K K H K K R S R S R S R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957462 366 41835 L183 F V A P P G L L I P P D V E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12297 963 106122 S764 P E M R L I G S T Q K D E E D
Honey Bee Apis mellifera XP_392191 993 109374 S794 E I G N S K P S S P Q D S S E
Nematode Worm Caenorhab. elegans Q10580 749 86291 N566 G P S D T T A N F S D I S G L
Sea Urchin Strong. purpuratus XP_001193164 899 100856 S716 A S A S Q E R S V Q V E R R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.4 89.6 N.A. 88.9 74.5 N.A. 80.4 80 N.A. 27.7 N.A. 26.3 22.3 24 30.4
Protein Similarity: 100 99.2 98.5 93.2 N.A. 93.2 78.6 N.A. 86 87.5 N.A. 32.5 N.A. 43 39 40 46
P-Site Identity: 100 100 20 26.6 N.A. 20 20 N.A. 13.3 20 N.A. 0 N.A. 0 0 6.6 6.6
P-Site Similarity: 100 100 33.3 53.3 N.A. 33.3 33.3 N.A. 40 33.3 N.A. 6.6 N.A. 26.6 20 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 0 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 8 24 0 0 8 % D
% Glu: 16 16 0 0 0 8 0 0 0 0 0 8 8 16 8 % E
% Phe: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 8 8 0 0 0 0 0 0 8 0 % G
% His: 0 16 0 0 31 0 8 8 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 8 0 0 8 0 0 0 % I
% Lys: 54 31 54 62 16 54 39 8 16 8 8 0 0 16 8 % K
% Leu: 0 0 0 0 8 0 8 8 0 0 0 0 0 0 16 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 8 8 0 8 0 0 16 8 0 16 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 16 8 0 0 0 0 % Q
% Arg: 0 8 8 8 16 0 24 31 16 39 24 39 16 47 8 % R
% Ser: 0 8 8 8 8 16 0 24 39 24 16 24 47 8 39 % S
% Thr: 0 0 0 0 8 8 0 16 8 0 24 0 8 8 0 % T
% Val: 0 8 0 0 0 0 0 0 8 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _