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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD3 All Species: 10.61
Human Site: S1522 Identified Species: 19.44
UniProt: Q12873 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12873 NP_001005271.2 2000 226592 S1522 P E L M P D P S A D S K R S S
Chimpanzee Pan troglodytes XP_512012 1846 210165 G1462 M R H L C E P G A D G S E T F
Rhesus Macaque Macaca mulatta XP_001111066 1981 224269 S1504 P E L M P D P S A D S K R S S
Dog Lupus familis XP_536627 1977 223828 S1499 P E L M P D P S A D S K R S S
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 E1519 P E L A E V E E N K K M S Q P
Rat Rattus norvegicus Q9JIX5 2581 290674 A1960 P D F S F L A A R M N Y M Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 G2136 K N F A Q N R G T G N A N T V
Frog Xenopus laevis NP_001080504 1893 214670 V1497 M S L I R K K V Q E F E H V N
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 R1766 G E I C V E D R S A P M Q V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 C1521 P E L I L K P C E P V R S A L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 V1369 M R H L C E P V V D N S D S F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 H1000 Y G I L F L K H I A E E I D E
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 T1083 E K L E K H A T A Y R A K L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 97.8 97.3 N.A. 67.6 22.6 N.A. N.A. 23.4 66 22.7 N.A. 55 N.A. 47.2 N.A.
Protein Similarity: 100 90.5 98.1 98 N.A. 78.3 37.6 N.A. N.A. 37.2 77.1 38.5 N.A. 68.6 N.A. 61.7 N.A.
P-Site Identity: 100 20 100 100 N.A. 20 6.6 N.A. N.A. 0 6.6 6.6 N.A. 26.6 N.A. 20 N.A.
P-Site Similarity: 100 40 100 100 N.A. 20 33.3 N.A. N.A. 20 33.3 33.3 N.A. 46.6 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 26 N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 16 8 39 16 0 16 0 8 0 % A
% Cys: 0 0 0 8 16 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 24 8 0 0 39 0 0 8 8 0 % D
% Glu: 8 47 0 8 8 24 8 8 8 8 8 16 8 0 16 % E
% Phe: 0 0 16 0 16 0 0 0 0 0 8 0 0 0 16 % F
% Gly: 8 8 0 0 0 0 0 16 0 8 8 0 0 0 0 % G
% His: 0 0 16 0 0 8 0 8 0 0 0 0 8 0 0 % H
% Ile: 0 0 16 16 0 0 0 0 8 0 0 0 8 0 0 % I
% Lys: 8 8 0 0 8 16 16 0 0 8 8 24 8 0 8 % K
% Leu: 0 0 54 24 8 16 0 0 0 0 0 0 0 8 8 % L
% Met: 24 0 0 24 0 0 0 0 0 8 0 16 8 0 0 % M
% Asn: 0 8 0 0 0 8 0 0 8 0 24 0 8 0 16 % N
% Pro: 47 0 0 0 24 0 47 0 0 8 8 0 0 0 8 % P
% Gln: 0 0 0 0 8 0 0 0 8 0 0 0 8 16 0 % Q
% Arg: 0 16 0 0 8 0 8 8 8 0 8 8 24 0 0 % R
% Ser: 0 8 0 8 0 0 0 24 8 0 24 16 16 31 24 % S
% Thr: 0 0 0 0 0 0 0 8 8 0 0 0 0 16 0 % T
% Val: 0 0 0 0 8 8 0 16 8 0 8 0 0 16 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _