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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD3 All Species: 7.27
Human Site: S21 Identified Species: 13.33
UniProt: Q12873 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12873 NP_001005271.2 2000 226592 S21 K N D Q L R I S F P P G L C W
Chimpanzee Pan troglodytes XP_512012 1846 210165 R25 G A P E H R R R W V A S S Y T
Rhesus Macaque Macaca mulatta XP_001111066 1981 224269 S21 K N D Q L R I S F P P G L C W
Dog Lupus familis XP_536627 1977 223828 S21 D D I R L L P S A L G V K K R
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 D21 G S E E E D M D A L L N N S L
Rat Rattus norvegicus Q9JIX5 2581 290674 E34 Q V T Q D P I E E A L G L P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 T67 N Q N Q A K L T H F D H Y N Q
Frog Xenopus laevis NP_001080504 1893 214670 N21 G E I E V M L N S S I H Q D D
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 E34 Q G S S D P V E E A L K L A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 N21 E E E A Q E D N A P A A E L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 L21 T M E E D S M L A E G H E D G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 97.8 97.3 N.A. 67.6 22.6 N.A. N.A. 23.4 66 22.7 N.A. 55 N.A. 47.2 N.A.
Protein Similarity: 100 90.5 98.1 98 N.A. 78.3 37.6 N.A. N.A. 37.2 77.1 38.5 N.A. 68.6 N.A. 61.7 N.A.
P-Site Identity: 100 6.6 100 13.3 N.A. 0 26.6 N.A. N.A. 6.6 0 6.6 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 20 100 26.6 N.A. 26.6 33.3 N.A. N.A. 33.3 26.6 20 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 26 N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 0 0 31 16 16 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % C
% Asp: 8 8 16 0 24 8 8 8 0 0 8 0 0 16 8 % D
% Glu: 8 16 24 31 8 8 0 16 16 8 0 0 16 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 16 8 0 0 0 0 0 % F
% Gly: 24 8 0 0 0 0 0 0 0 0 16 24 0 0 8 % G
% His: 0 0 0 0 8 0 0 0 8 0 0 24 0 0 0 % H
% Ile: 0 0 16 0 0 0 24 0 0 0 8 0 0 0 0 % I
% Lys: 16 0 0 0 0 8 0 0 0 0 0 8 8 8 0 % K
% Leu: 0 0 0 0 24 8 16 8 0 16 24 0 31 8 16 % L
% Met: 0 8 0 0 0 8 16 0 0 0 0 0 0 0 0 % M
% Asn: 8 16 8 0 0 0 0 16 0 0 0 8 8 8 0 % N
% Pro: 0 0 8 0 0 16 8 0 0 24 16 0 0 8 0 % P
% Gln: 16 8 0 31 8 0 0 0 0 0 0 0 8 0 8 % Q
% Arg: 0 0 0 8 0 24 8 8 0 0 0 0 0 0 8 % R
% Ser: 0 8 8 8 0 8 0 24 8 8 0 8 8 8 16 % S
% Thr: 8 0 8 0 0 0 0 8 0 0 0 0 0 0 8 % T
% Val: 0 8 0 0 8 0 8 0 0 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 16 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _