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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD3 All Species: 13.64
Human Site: S272 Identified Species: 25
UniProt: Q12873 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12873 NP_001005271.2 2000 226592 S272 G P G H K R R S K S P R V P D
Chimpanzee Pan troglodytes XP_512012 1846 210165 S271 G P G H K R R S K S P R V P D
Rhesus Macaque Macaca mulatta XP_001111066 1981 224269 S272 G P G H K R R S K S P R V P D
Dog Lupus familis XP_536627 1977 223828 S250 G P G H K R R S K S P R V P D
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 P279 R V P D A K K P K P K K V A P
Rat Rattus norvegicus Q9JIX5 2581 290674 R286 P A Q G E S K R I T L V L Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 G336 T G M N Q N L G L T N N T P M
Frog Xenopus laevis NP_001080504 1893 214670 P264 G P N A R K K P K V V R P P E
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 L401 R L A V P L K L L L Q P Q S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 R264 G R G K K G R R P S G K V P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 N231 G K E E A R I N R A A A K V D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 Q30 H R A A A H Q Q N Y F N D S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 97.8 97.3 N.A. 67.6 22.6 N.A. N.A. 23.4 66 22.7 N.A. 55 N.A. 47.2 N.A.
Protein Similarity: 100 90.5 98.1 98 N.A. 78.3 37.6 N.A. N.A. 37.2 77.1 38.5 N.A. 68.6 N.A. 61.7 N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 0 N.A. N.A. 6.6 33.3 0 N.A. 46.6 N.A. 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 33.3 26.6 N.A. N.A. 26.6 60 13.3 N.A. 53.3 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 26 N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 16 24 0 0 0 0 8 8 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 47 % D
% Glu: 0 0 8 8 8 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 54 8 39 8 0 8 0 8 0 0 8 0 0 0 0 % G
% His: 8 0 0 31 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 39 16 31 0 47 0 8 16 8 0 0 % K
% Leu: 0 8 0 0 0 8 8 8 16 8 8 0 8 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 8 8 0 8 0 8 8 0 8 16 0 0 8 % N
% Pro: 8 39 8 0 8 0 0 16 8 8 31 8 8 54 8 % P
% Gln: 0 0 8 0 8 0 8 8 0 0 8 0 8 8 8 % Q
% Arg: 16 16 0 0 8 39 39 16 8 0 0 39 0 0 0 % R
% Ser: 0 0 0 0 0 8 0 31 0 39 0 0 0 16 0 % S
% Thr: 8 0 0 0 0 0 0 0 0 16 0 0 8 0 8 % T
% Val: 0 8 0 8 0 0 0 0 0 8 8 8 47 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _