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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD3 All Species: 27.88
Human Site: Y1050 Identified Species: 51.11
UniProt: Q12873 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12873 NP_001005271.2 2000 226592 Y1050 P K L P S G A Y E G G A L I K
Chimpanzee Pan troglodytes XP_512012 1846 210165 Y1045 P K L P S G A Y E G G A L I K
Rhesus Macaque Macaca mulatta XP_001111066 1981 224269 Y1032 P K L P S G A Y E G G A L I K
Dog Lupus familis XP_536627 1977 223828 Y1027 P K L P S G A Y E G G A L I K
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 Y1033 P K M P N G M Y D G S A L I R
Rat Rattus norvegicus Q9JIX5 2581 290674 F1123 C H I I P Q D F H L Q A M V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 F1281 H N A D S P D F Q L Q A M I Q
Frog Xenopus laevis NP_001080504 1893 214670 Y1031 P K M P N G M Y D G S A L I K
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 Y1153 V S E L R E V Y D P L A P D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 Y1042 T T A A G G L Y E I N S L T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 Y930 P K L K N G M Y E G S A L I K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 C594 F K Q L L E S C G K L Q L L D
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 G677 E R V L Q K F G D G K M T R E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 97.8 97.3 N.A. 67.6 22.6 N.A. N.A. 23.4 66 22.7 N.A. 55 N.A. 47.2 N.A.
Protein Similarity: 100 90.5 98.1 98 N.A. 78.3 37.6 N.A. N.A. 37.2 77.1 38.5 N.A. 68.6 N.A. 61.7 N.A.
P-Site Identity: 100 100 100 100 N.A. 60 6.6 N.A. N.A. 20 66.6 13.3 N.A. 33.3 N.A. 73.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 40 N.A. N.A. 46.6 86.6 20 N.A. 40 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 26 N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 0 31 0 0 0 0 77 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 16 0 31 0 0 0 0 8 8 % D
% Glu: 8 0 8 0 0 16 0 0 47 0 0 0 0 0 8 % E
% Phe: 8 0 0 0 0 0 8 16 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 8 62 0 8 8 62 31 0 0 0 0 % G
% His: 8 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 8 0 0 0 62 0 % I
% Lys: 0 62 0 8 0 8 0 0 0 8 8 0 0 0 54 % K
% Leu: 0 0 39 24 8 0 8 0 0 16 16 0 70 8 0 % L
% Met: 0 0 16 0 0 0 24 0 0 0 0 8 16 0 0 % M
% Asn: 0 8 0 0 24 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 54 0 0 47 8 8 0 0 0 8 0 0 8 0 0 % P
% Gln: 0 0 8 0 8 8 0 0 8 0 16 8 0 0 8 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 0 0 0 8 16 % R
% Ser: 0 8 0 0 39 0 8 0 0 0 24 8 0 0 0 % S
% Thr: 8 8 0 0 0 0 0 0 0 0 0 0 8 8 0 % T
% Val: 8 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _